Modelling the relationship between malaria prevalence as a measure of transmission and mortality across age groups (Publications)
BACKGROUND: Parasite prevalence has been used widely as a measure of malaria transmission, especially in malaria endemic areas. However, its contribution and relationship to malaria mortality across d
Exposure to nonmicrobial N-glycolylneuraminic acid protects farmers' children against airway inflammation and colitis (Publications)
BACKGROUND: Childhood exposure to a farm environment has been shown to protect against the development of inflammatory diseases, such as allergy, asthma, and inflammatory bowel disease. OBJECTIVE: We
Insight into potassium's role in childhood mortality due to severe acute malnutrition (Publications)
Hypokalaemia is associated with an increase in mortality in children with severe acute malnutrition (SAM) and diarrhoea. This is a descriptive cross-sectional retrospective study conducted in the Nutr
Therapeutic efficacy of albendazole against soil-transmitted helminthiasis in children measured by five diagnostic methods (Publications)
BACKGROUND: Preventive chemotherapy (PC) with benzimidazole drugs is the backbone of soil-transmitted helminth (STH) control programs. Over the past decade, drug coverage has increased and with it, th
Modelling reactive case detection strategies for interrupting transmission of <em>Plasmodium falciparum</em> malaria (Publications)
BACKGROUND: As areas move closer to malaria elimination, a combination of limited resources and increasing heterogeneity in case distribution and transmission favour a shift to targeted reactive inter
Theory of reactive interventions in the elimination and control of malaria (Publications)
BACKGROUND: Reactive case detection (RCD) is an integral part of many malaria control and elimination programmes and can be conceived of as a way of gradually decreasing transmission. However, it is u
<em>N</em>-substituted noscapine derivatives as new antiprotozoal agents: synthesis, antiparasitic activity and molecular docking study (Publications)
Novel N-substituted noscapine derivatives were synthesized by a three-component Strecker reaction of cyclic ether of N-nornoscapine with varied aldehydes, in the presence of cyanide ion. Moreover, the