Randomized trial to improve children's body composition and micronutrient status among South African Children (Publications)
INTRODUCTION: Physical activity (PA) promotion combined with multi-micronutrient supplementation (MMNS) among school-age children may reduce fat mass accrual and increase muscle mass through different
Investigations of the metabolites of the trypanocidal drug melarsoprol (Publications)
BACKGROUND: Melarsoprol remains the first-choice drug for trypanosomiasis (human African sleeping sickness). To contribute to the sparse pharmacologic data and to better understand the cause of the fr
Healthcare professional and professional stakeholders' perspectives on vaccine mandates in Switzerland: a mixed-methods study (Publications)
BACKGROUND: There currently are no mandatory vaccines in Switzerland. However, Swiss federal legislation allows for vaccination mandates in settings where the risk of transmission to vulnerable groups
Pharmacokinetic modelling and simulation to optimize albendazole dosing in hookworm- or <em>Trichuris trichiura</em>-infected infants to adults (Publications)
BACKGROUND: Albendazole is the most commonly used drug in preventive chemotherapy programmes against soil-transmitted helminth (STH) infections, with the standard dose of 400 mg resulting in suboptima
Equity in health insurance schemes enrollment in low and middle-income countries: a systematic review and meta-analysis (Publications)
BACKGROUND: Ensuring access to essential quality health services and reducing financial hardship for all individuals regardless of their ability to pay are the main goals of universal health coverage.
Effects of a partially supervised conditioning program in cystic fibrosis: an international multicenter, randomized controlled trial (ACTIVATE-CF) (Publications)
Rationale: The long-term effects of vigorous physical activity (PA) on lung function in cystic fibrosis are unclear. Objectives: To evaluate effects of a 12-month partially supervised PA intervention
Multi-insecticide resistant malaria vectors in the field remain susceptible to malathion, despite the presence of <em>Ace1</em> point mutations (Publications)
Insecticide resistance in Anopheles mosquitoes is seriously threatening the success of insecticide-based malaria vector control. Surveillance of insecticide resistance in mosquito populations and iden
Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1β, are linked to fibrin formation in... (Publications)
Buruli ulcer (BU) is a neglected tropical disease caused by subcutaneous infection with Mycobacterium ulcerans and its exotoxin mycolactone. BU displays coagulative necrosis and widespread fibrin depo