Explaining patient delay in healthcare seeking and loss to diagnostic follow-up among patients with presumptive tuberculosis in Tanzania: a... (Publications)
BACKGROUND: Delay in healthcare seeking and loss to diagnostic follow-up (LDFU) contribute to substantial increase in tuberculosis (TB) morbidity and mortality. We examined factors, including perceive
Screening strategy for Chagas disease in a non-endemic country (Switzerland): a prospective evaluation (Publications)
The WHO recommends screening of Latin American migrants for Chagas disease to reduce morbidity and mortality and increase the likelihood of eradicating the disease. The objective was to assess the fea
Multicentre assessment of motor and sensory evoked potentials in multiple sclerosis: reliability and implications for clinical trials (Publications)
Background: Motor and sensory evoked potentials (EP) are potential candidate biomarkers for clinical trials in multiple sclerosis. Objective: To determine test -retest reliability of motor EP (MEP) an
Genetic diversity of <em>Mycobacterium tuberculosis</em> strains circulating in Botswana (Publications)
BACKGROUND: Molecular typing of Mycobacterium tuberculosis (M.tb) isolates can inform Tuberculosis (TB) control programs on the relative proportion of transmission driving the TB epidemic. There is li
Demand-side financing in the form of baby packages in Northern Mozambique: results from an observational study (Publications)
BACKGROUND: The Maternal Mortality Ratio in Mozambique has stagnated at 405 deaths per 100,000 live births with virtually no progress over the last 15 years. Low Institutional Birth Rates (IBRs) level
Epigenome-wide association study of lung function level and its change (Publications)
Previous reports link differential DNA methylation (DNAme) to environmental exposures which are associated with lung function. Direct evidence on lung function DNAme is however limited. We undertook a
Single pivotal trials with few corroborating characteristics were used for FDA approval of cancer therapies (Publications)
INTRODUCTION: Novel cancer therapies are often approved with evidence from a single pivotal trial alone. There are concerns about the credibility of this evidence. Higher validity may be indicated by