<em>In vitro</em> and <em>in vivo</em> trematode models for chemotherapeutic studies (Publications)
SUMMARYSchistosomiasis and food-borne trematodiases are chronic parasitic diseases affecting millions of people mostly in the developing world. Additional drugs should be developed as only few drugs a
The Maurer's cleft protein MAHRP1 is essential for trafficking of PfEMP1 to the surface of <em>Plasmodium falciparum</em>-infected erythrocytes (Publications)
During the intra-erythrocytic development of Plasmodium falciparum, the parasite modifies the host cell surface by exporting proteins that interact with or insert into the erythrocyte membrane. These
Estimating the health and economic benefits associated with reducing air pollution in the Barcelona metropolitan area (Spain) (Publications)
OBJECTIVES: To estimate the health and economic benefits that would result from two scenarios of improved air quality in 57 municipalities of the metropolitan area of Barcelona. METHODS: We used attri
Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase (Publications)
We report the discovery of novel uracil-based acyclic compounds as inhibitors of deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase), an enzyme involved in nucleotide metabolism that has been i
Novel inhibitors of leishmanial dihydrofolate reductase (Publications)
The program DOCK3.5 was used to search the Cambridge Structural Database for novel inhibitors of Leishmanial dihydrofolate reductase. A number of compounds were obtained and screened against the enzym