The contribution of reduction in malaria as a cause of rapid decline of under-five mortality: evidence from the Rufiji Health and Demographic... (Publications)
BACKGROUND: Under-five mortality has been declining rapidly in a number of sub-Saharan African settings. Malaria-related mortality is known to be a major component of childhood causes of death and mal
Spatial distribution of heavy metals in soil, water, and vegetables of farms in Sanandaj, Kurdistan, Iran (Publications)
BACKGROUND: Heavy metals are ubiquitous elsewhere in nature and their measurement in environment is necessary to develop health management strategies. In this study, we aimed to find out concentration
Haemolytic activity in the blood clot of <em>Aedes aegypti</em> (Publications)
In the present study it was demonstrated that mosquito blood clots contain a haemolytic principle which achieves haemolysis of washed erythrocytes in an isotonic medium. Proteinases are thought to pla
A new double-antibody sandwich ELISA targeting <em>Plasmodium falciparum</em> aldolase to evaluate anti-malarial drug sensitivity (Publications)
BACKGROUND: The standard in vitro test to assess anti-malarial activity of chemical compounds is the [3H]hypoxanthine incorporation assay. It is a radioactivity-based method to measure DNA replication
A research agenda for malaria eradication: vector control (Publications)
Different challenges are presented by the variety of malaria transmission environments present in the world today. In each setting, improved control for reduction of morbidity is a necessary first ste
Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism (Publications)
BACKGROUND AND METHODOLOGY: Recently, we reported on a new class of naphthoquinone derivatives showing a promising anti-trypanosomatid profile in cell-based experiments. The lead of this series (B6, 2