MER41 repeat sequences contain inducible STAT1 binding sites (Publications)
Chromatin immunoprecipitation combined with massively parallel sequencing methods (ChIP-seq) is becoming the standard approach to study interactions of transcription factors (TF) with genomic sequence
Spatially-explicit risk profiling of<em> Plasmodium falciparum</em> infections at a small scale: a geostatistical modelling approach (Publications)
BACKGROUND: There is a renewed political will and financial support to eradicate malaria. Spatially-explicit risk profiling will play an important role in this endeavour. Patterns of Plasmodium falcip
High sensitivity detection of <em>Plasmodium</em> species reveals positive correlations between infections of different species, shifts in age... (Publications)
BACKGROUND: When diagnosed by standard light microscopy (LM), malaria prevalence can vary significantly between sites, even at local scale, and mixed species infections are consistently less common th
Ensemble modeling of the likely public health impact of a pre-erythrocytic malaria vaccine (Publications)
BACKGROUND: The RTS,S malaria vaccine may soon be licensed. Models of impact of such vaccines have mainly considered deployment via the World Health Organization's Expanded Programme on Immunization (
Dynamics of <em>Schistosoma haematobium</em> egg output and associated infection parameters following treatment with praziquantel in school-aged... (Publications)
ABSTRACT: BACKGROUND: Praziquantel is the drug of choice in preventive chemotherapy targeting schistosomiasis. Increasing large-scale administration of praziquantel requires monitoring of drug efficac
Improving community coverage of oral cholera mass vaccination campaigns: lessons learned in Zanzibar (Publications)
BACKGROUND: Recent research in two cholera-endemic communities of Zanzibar has shown that a majority (?94%) of the adult population was willing to receive free oral cholera vaccines (OCVs). Since OCV
Effect of schistosomiasis and soil-transmitted helminth infections on physical fitness of school children in Côte d'Ivoire (Publications)
BACKGROUND: Schistosomiasis and soil-transmitted helminthiasis are important public health problems in sub-Saharan Africa causing malnutrition, anemia, and retardation of physical and cognitive develo
Malaria knowledge and long-lasting insecticidal net use in rural communities of central Côte d'Ivoire (Publications)
BACKGROUND: To improve effectiveness of malaria control interventions, it is essential to deepen the knowledge of contextual factors that govern people's practice for preventive and curative measures.
Staff experiences of providing maternity services in rural southern Tanzania - a focus on equipment, drug and supply issues (Publications)
BACKGROUND: The poor maintenance of equipment and inadequate supplies of drugs and other items contribute to the low quality of maternity services often found in rural settings in low- and middle-inco