Evidence of blood stage efficacy with a virosomal malaria vaccine in a phase IIa clinical trial (Publications)
BACKGROUND: Previous research indicates that a combination vaccine targeting different stages of the malaria life cycle is likely to provide the most effective malaria vaccine. This trial was the firs
Analysing and recommending options for maintaining universal coverage with long-lasting insecticidal nets: the case of Tanzania in 2011 (Publications)
BACKGROUND: Tanzania achieved universal coverage with long-lasting insecticidal nets (LLINs) in October 2011, after three years of free mass net distribution campaigns and is now faced with the challe
A large scale gene-centric association study of lung function in newly-hired female cotton textile workers with endotoxin exposure (Publications)
BACKGROUND: Occupational exposure to endotoxin is associated with decrements in pulmonary function, but how much variation in this association is explained by genetic variants is not well understood.
Malaria surveillance-response strategies in different transmission zones of the People's Republic of China: preparing for climate change (Publications)
ABSTRACT: BACKGROUND: A sound understanding of malaria transmission patterns in the People's Republic of China (P.R. China) is crucial for designing effective surveillance-response strategies that can
Mefloquine - an aminoalcohol with promising antischistosomal properties in mice (Publications)
BACKGROUND: The treatment and control of schistosomiasis, an often neglected tropical disease that exacerbates poverty, depends on a single drug, praziquantel. The large-scale use of praziquantel migh
Differential patterns of infection and disease with <em>P. falciparum</em> and <em>P. vivax</em> in young Papua New Guinean children (Publications)
BACKGROUND: Where P. vivax and P. falciparum occur in the same population, the peak burden of P. vivax infection and illness is often concentrated in younger age groups. Experiences from malaria thera
PM2.5 and NO2 assessment in 21 European study centres of ECRHS II: annual means and seasonal differences (Publications)
The follow-up of cohorts of adults from more than 20 European centres of the former ECRHS I (1989-1992) investigates long-term effects of exposure to ambient air pollution on respiratory health, in pa
Association of STR polymorphisms in CMA1 and IL-4 with asthma and atopy: the SAPALDIA cohort (Publications)
Asthma is a chronic pulmonary disorder that is characterized by airway inflammation and bronchial hyperreactivity. Several genetic loci have been associated with asthma, and some of these associations
A sigmoidoscopy-based case-control study of polyps: macronutrients, fiber and meat consumption (Publications)
We conducted a large, sigmoidoscopy-based case-control study to examine the relation of intake of macronutrients, meat, and fiber to occurrence of adenomas of the large bowel. Cases were subjects diag