The role of <em>Trypanosoma brucei</em> MRPA in melarsoprol susceptibility (Publications)
We previously showed that over-expression of Trypanosoma brucei MRPA, a member of the multidrug resistance protein family in T. brucei, reproducibly resulted in resistance to the anti-trypanosomal dru
Design and synthesis of a series of melamine-based nitroheterocycles with activity against trypanosomatid parasites (Publications)
The parasites that give rise to human African trypanosomiasis (HAT) are auxotrophs for various nutrients from the human host, including purines. They have specialist nucleoside transporters to import
Synthesis and antiprotozoal activity of cationic 1,4-diphenyl-1<em>H</em>-1,2,3-triazoles (Publications)
Novel dicationic triazoles 1-60 were synthesized by the Pinner method from the corresponding dinitriles, prepared via the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC). The type and the place
Prevalence and implications of multiple-strain infections (Publications)
Infections frequently contain multiple strains (genotypes) of the same pathogen, yet they are still usually treated as uniform entities. In this Review, we discuss problems with inconsistent definitio
Predictors and overestimation of recalled mobile phone use among children and adolescents (Publications)
A growing body of literature addresses possible health effects of mobile phone use in children and adolescents by relying on the study participants' retrospective reconstruction of mobile phone use. I
Allergic diseases and atopic sensitization in children related to farming and anthroposophic lifestyle - the PARSIFAL study (Publications)
Background: The prevalence of allergic diseases has increased rapidly in recent decades, particularly in children. For adequate prevention it is important not only to identify risk factors, but also p