Prioritization of prevention activities to combat the spread of HIV/AIDS in resource constrained settings: a cost-effectiveness analysis from Chad,... (Publications)
In Chad, as in most sub-Saharan Africa countries, HIV/AIDS poses a massive public health threat as well as an economic burden, with prevalence rates estimated at 9% of the adult population. In definin
<em>In vitro</em> and <em>in vivo</em> activity of 3-alkoxy-1,2-dioxolanes against <em>Schistosoma mansoni</em> (Publications)
OBJECTIVES: Compounds characterized by a peroxidic skeleton are an interesting starting point for antischistosomal drug discovery. Previously a series of 3-alkoxy-1,2-dioxolanes, which are chemically
Parental occupational exposure to extremely low frequency magnetic fields and childhood cancer: a German case-control study (Publications)
Extremely low frequency magnetic fields (ELF-MFs) have been classified as possibly carcinogenic to humans by the International Agency for Research on Cancer. The authors investigated, in a population-
Searching for new cures for tuberculosis: design, synthesis, and biological evaluation of 2-methylbenzothiazoles (Publications)
The actual development and clinical use of new therapeutics for tuberculosis (TB) have remained stagnant for years because of the complexity of the disease process, the treatment of which at present r
Measuring in-cabin school bus tailpipe and crankcase PM2.5: a new dual tracer method (Publications)
Exposures of occupants in school buses to on-road vehicle emissions, including emissions from the bus itself, can be substantially greater than those in outdoor settings. A dual tracer method was deve
Are environmental medicine problems relevant in Switzerland? (Publications)
BACKGROUND AND AIM: In Switzerland, the prevalence of health problems attributed to environmental exposures is unknown, and views differ regarding its magnitude. In the present study we investigated t
<em>Trypanothione reductase</em> high-throughput screening campaign identifies novel classes of inhibitors with anti-parasitic activity (Publications)
A high-throughput screening campaign of 100,000 lead like compounds led to the identification of 9 novel chemical classes of trypanothione reductase (TR) inhibitors worthy of further investigation. Hi