Safety, pharmacokinetic, and efficacy studies of oral DB868 in a first stage vervet monkey model of human African trypanosomiasis (Publications)
There are no oral drugs for human African trypanosomiasis (HAT, sleeping sickness). A successful oral drug would have the potential to reduce or eliminate the need for patient hospitalization, thus re
Identification of new PNEPs indicates a substantial non-PEXEL exportome and underpins common features in<em> Plasmodium falciparum</em> protein export (Publications)
Malaria blood stage parasites export a large number of proteins into their host erythrocyte to change it from a container of predominantly hemoglobin optimized for the transport of oxygen into a niche
Modeling the public health impact of malaria vaccines for developers and policymakers (Publications)
BACKGROUND: Efforts to develop malaria vaccines show promise. Mathematical model-based estimates of the potential demand, public health impact, and cost and financing requirements can be used to infor
Global health initiative investments and health systems strengthening: a content analysis of global fund investments (Publications)
BACKGROUND: Millions of dollars are invested annually under the umbrella of national health systems strengthening. Global health initiatives provide funding for low- and middle-income countries throug
Cancer survivors in Switzerland: a rapidly growing population to care for (Publications)
BACKGROUND: Cancer survivors are a heterogeneous group with complex health problems. Data concerning its total number and growing dynamics for Switzerland are scarce and outdated. METHODS: Population