Using human rights to improve maternal and neonatal health: history, connections and a proposed practical approach (Publications)
We describe the historical development of how maternal and neonatal mortality in the developing world came to be seen as a public-health concern, a human rights concern, and ultimately as both, leadin
High prevalence of <em>Strongyloides stercoralis</em> among school children in rural Côte d'Ivoire (Publications)
Two cross-sectional surveys were carried out in rural Cote d'Ivoire, the first in 5 primary schools in the Lake Taabo area, and the second in the primary school of Azaguie-Institute de Recherche sur l
In vivo investigations of selected diamidine compounds against <em>Trypanosoma evansi</em> using a mouse model (Publications)
Surra is an animal pathogenic protozoan infection, caused by Trypanosoma evansi, that develops into a fatal wasting disease. Control measures rely on diagnosis and treatment. However, with the continu
<em>myo</em>-inositol uptake is essential for bulk inositol phospholipid but not glycosylphosphatidylinositol synthesis in <em>Trypanosoma brucei</em> (Publications)
myo-Inositol is an essential precursor for the production of inositol phosphates and inositol phospholipids in all eukaryotes. Intracellular myo-inositol is generated by de novo synthesis from glucose
A "one health" surveillance and control of brucellosis in developing countries: moving away from improvisation (Publications)
Although a "One Health" approach has been successfully implemented for emerging infectious zoonotic diseases with pandemic potential, we still lack a conceptual framework to address enzootic diseases
Structure-activity relationship studies of orally active antimalarial 3,5-substituted 2-aminopyridines (Publications)
In an effort to address potential cardiotoxicity liabilities identified with earlier frontrunner compounds, a number of new 3,5-diaryl-2-aminopyridine derivatives were synthesized. Several compounds e
SAR studies on azasterols as potential anti-trypanosomal and anti-leishmanial agents (Publications)
There is an urgent need for the development of new drugs for the treatment of neglected tropical diseases such as human African trypanosomiasis, Chagas disease and leishmaniasis. Azasterols, have been