Liver morbidity due to <em>Schistosoma mekongi</em> in Cambodia after seven rounds of mass drug administration (Publications)
Severe liver disease due to Schistosoma mekongi was frequent in northern Cambodia. Between 1995 and 2002, seven rounds of mass chemotherapy (praziquantel) reduced infection from 50% to below 3%. In 20
Activity of antiandrogens against juvenile and adult <em>Schistosoma mansoni </em>in mice (Publications)
Objectives The antischistosomal properties of the marketed antiandrogens bicalutamide, flutamide, nilutamide and cyproterone acetate were studied both in vivo and in vitro. Methods Schistosoma mansoni
Tuberculosis control in refugee populations: a challenge to both relief agencies and national programs (Publications)
Today's worldwide tuberculosis epidemic and the movement of a growing number of refugees overlap geographically and have made tuberculosis control in refugee populations an issue of increasing importa
Evaluation of quinolone derivatives for antitrypanosomal activity (Publications)
About 160 fluoroquinolones and derivatives were tested for antitrypanosomal activity in a drug sensitivity assay followed by fluorometric evaluation. The most active quinolone compounds had IC50 value
Heteronuclear 19F-1H statistical total correlation spectroscopy as a tool in drug metabolism: study of flucloxacillin biotransformation (Publications)
We present a novel application of the heteronuclear statistical total correlation spectroscopy (HET-STOCSY) approach utilizing statistical correlation between one-dimensional 19F/1H NMR spectroscopic
Interactions of mefloquine with praziquantel in the <em>Schistosoma mansoni</em> mouse model and <em>in vitro</em> (Publications)
Objectives Mefloquine has interesting antischistosomal properties, hence it might be an attractive partner drug for combination treatment with praziquantel. The aim of this study was to evaluate activ