Ribosomal protein S6 is hyper-activated and differentially phosphorylated in epidermal lesions of patients with psoriasis and atopic dermatitis (Publications)
BACKGROUND: The ribosomal protein S6 (S6) is part of the translation machinery and activated by phosphorylation via the mammalian target of rapamycin (mTOR) pathway, which is activated in psoriatic sk
Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function (Publications)
Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)-7-like cytokine, mainly expressed by epithelial cells, and key to the development of allergic responses. The well-documented involvement of T
Lipidomics identifies a requirement for peroxisomal function during influenza virus replication (Publications)
Influenza virus acquires a host-derived lipid envelope during budding, yet a convergent view on the role of host lipid metabolism during infection is lacking. Using a mass spectrometry-based lipidomic
Relationship between domain-specific physical activity and different body composition measures in a working population (Publications)
OBJECTIVE: With respect to the overweight epidemic, this study aimed to investigate the association between domain-specific physical activity and body composition measures in Swiss male employees. MET
Generation of chimeric monoclonal antibodies from mice that carry human immunoglobulin Cgamma1 heavy of Ckappa light chain gene segments (Publications)
Gene targeting in mouse embryonic stem (ES) cells was used to replace (i) the mouse immunoglobulin heavy chain (IgH) Cgamma2a gene segment (mCgamma2a) with the human Cgamma1 gene segment (hCgamma1), a