A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants (Publications)
Background The candidate malaria vaccine RTS,S/AS01 reduced episodes of both clinical and severe malaria in children 5 to 17 months of age by approximately 50% in an ongoing phase 3 trial. We studied
The comparative antimalarial properties of weak base and neutral synthetic ozonides (Publications)
Thirty-three N-acyl 1,2,4-dispiro trioxolanes (secondary ozonides) were synthesized. For these ozonides, weak base functional groups were not required for high antimalarial potency against Plasmodium
Levels of physical activity and sedentary time among 10- to 12-year-old boys and girls across 5 European countries using accelerometers: an... (Publications)
ABSTRACT: BACKGROUND: The study aim was to objectively assess levels of sedentary time, light, moderate and vigorous physical activity (PA) among 10-12 year olds across five European countries and to
Short-term effects of particulate matter on total mortality during Saharan dust outbreaks: a case-crossover analysis in Madrid (Spain) (Publications)
BACKGROUND: The role of Saharan dust outbreaks on the relationship between particulate matter and daily mortality has recently been addressed in studies conducted in Southern Europe, although they hav
Evaluation des Aktionstages "Basel bewegt - fit und gesund unterwegs" vom 22. September 2004 (Publications)
Das Projekt ‚Basel bewegt, fit und gesund unterwegs’ leistete einen Beitrag zum europäischen Aktionstag ‚In die Stadt ohne mein Auto’. Die Stadt Basel beteiligte sich bereits zum fünften Mal daran. Di
2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage <em>Plasmodium</em> infections (Publications)
Acetylenic fatty acids are known to display several biological activities, but their antimalarial activity has remained unexplored. In this study, we synthesized the 2-, 5-, 6-, and 9-hexadecynoic aci
Association between short term exposure to fine particulate matter and heart rate variability in older subjects with and without heart disease (Publications)
BACKGROUND: Short term increases in exposure to particulate matter (PM) air pollution are associated with increased cardiovascular morbidity and mortality. The mechanism behind this effect is unclear,