Parasite-host dynamics throughout antimalarial drug development stages complicate the translation of parasite clearance (Publications)
Ensuring continued success against malaria depends on a pipeline of new antimalarials. Antimalarial drug development utilizes pre-clinical murine and experimental human malaria infection studies to ev
Investigation of heterochromatin protein 1 function in the malaria parasite <em>Plasmodium falciparum</em> using a conditional domain deletion and... (Publications)
The human malaria parasite Plasmodium falciparum encodes a single ortholog of heterochromatin protein 1 (PfHP1) that plays a crucial role in the epigenetic regulation of various survival-related proce
Efficacy of triclabendazole and albendazole against <em>Fasciola </em>spp. infection in cattle in Côte d'Ivoire: a randomised blinded trial (Publications)
Triclabendazole is the anthelminthic of choice for the treatment of fascioliasis, however, it is not yet registered in many countries. Therefore, we investigated the efficacy of a single-dose of tricl
Enantiospecific antitrypanosomal<em> in vitro</em> activity of eflornithine (Publications)
The polyamine synthesis inhibitor eflornithine is a recommended treatment for the neglected tropical disease Gambian human African trypanosomiasis in late stage. This parasitic disease, transmitted by
Expression dysregulation as a mediator of fitness costs in antibiotic resistance (Publications)
Antimicrobial resistance (AMR) poses a threat to global health and the economy. Rifampicin-resistant Mycobacterium tuberculosis accounts for a third of the global AMR burden. Gaining the upper hand on
"Linkage to care" among people living with HIV - definition in the era of "universal test and treat" in a sub-Sahara African setting (Publications)
BACKGROUND: Prompt linkage to human immunodeficiency virus (HIV) care after diagnosis is of utmost importance for individual health and reduction of HIV transmission. Different definitions for “linkag
Three-year rates of reoperation and revision following mobile versus fixed-bearing total ankle arthroplasty: a cohort of 302 patients with 2 implants... (Publications)
BACKGROUND: Currently, the implants utilized in total ankle arthroplasty (TAA) are divided between mobile-bearing 3-component and fixed-bearing 2-component designs. The literature evaluating the influ