Structure-activity-based design of a synthetic malaria peptide eliciting sporozoite inhibitory antibodies in a virosomal formulation (Publications)
The circumsporozoite protein (CSP) of Plasmodium falciparum is a leading candidate antigen for inclusion in a malaria subunit vaccine. We describe here the design of a conformationally constrained syn
First generation leishmaniasis vaccines: A review of field efficacy trials (Publications)
First generation candidate vaccines against leishmaniasis, prepared using inactivated whole parasites as their main ingredient, were considered as promising because of their relative ease of productio
Synthesis and antiprotozoal activity of <em>N</em>-alkoxy analogues of the trypanocidal lead compound 4,4'-bis(imidazolinylamino)diphenylamine with... (Publications)
To improve the blood-brain barrier permeability of the trypanocidal lead compound 4,4'-bis(imidazolinylamino)diphenylamine (1), five N-alkoxy analogues were synthesized from bis(4-isothiocyanatophenyl
Feasibility of future epidemiological studies on possible health effects of mobile phone base stations (Publications)
The increasing deployment of mobile communication base stations led to an increasing demand for epidemiological studies on possible health effects of radio frequency emissions. The methodological chal
Disparities in parasitic infections, perceived ill health and access to health care among poorer and less poor schoolchildren of rural Côte... (Publications)
Differences in the state of health between rural and urban populations living in Africa have been described, yet only few studies analysed inequities within poor rural communities. We investigated dis
Monitoring of 1-min personal particulate matter exposures in relation to voice-recorded time-activity data (Publications)
Recent studies on the association between exposures to airborne particulate matter (PM) and disease have identified short-term peaks in PM exposures as posing especial health threats. Lightweight pers
Lack of association between the polyadenylation polymorphism in the NAT1 (acetyltransferase 1) gene and colorectal adenomas (Publications)
Smoking and a high intake of red meat are risk factors for colorectal tumors. These effects could be due to aromatic amine carcinogens. Individual susceptibility to aromatic amines has been related to