Helminth infections, morbidity indicators, and schistosomiasis treatment history in three villages, Dongting Lake region, P.R. China (Publications)
In order to estimate the public health impact of helminth infections, and to provide baseline data for interventions, parasitological and morbidity surveys were conducted among inhabitants of three vi
Biobanking for epidemiological research and public health (Publications)
Almost all healthcare systems are currently facing fundamental challenges. New ways of organizing these systems based on novel knowledge and stakeholders' different needs are required to meet these ch
Cardiac involvement in African and American trypanosomiasis (Publications)
American trypanosomiasis (Chagas disease) and human African trypanosomiasis (HAT; sleeping sickness) are both caused by single-celled flagellates that are transmitted by arthropods. Cardiac problems a
Treatment of late stage sleeping sickness caused by <em>T.b. gambiense</em>: a new approach to the use of an old drug (Publications)
Melarsoprol is the standard treatment of late stage trypanosomiasis. The development of treatment schedules was previously purely empirical. Generally melarsoprol is given in 3 series of three to four
O-alkoxyamidine prodrugs of furamidine: in vitro transport and microsomal metabolism as indicators of in vivo efficacy in a mouse model of... (Publications)
Five O-alkoxyamidine analogues of the prodrug 2,5-bis[4-methoxyamidinophenyl]furan were synthesized and evaluated against Trypanosoma brucei rhodesiense in the STIB900 mouse model by oral administrati