Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy (Publications)
Aminoacyl transfer RNA (tRNA) synthetases (aaRSs) are attractive drug targets, and we present class I and II aaRSs as previously unrecognized targets for adenosine 5'-monophosphate-mimicking nucleosid
Lung allograft microbiome association with gastroesophageal reflux, inflammation, and allograft dysfunction (Publications)
RATIONALE: It remains unclear how gastroesophageal reflux disease (GERD) affects allograft microbial community composition in lung transplant recipients, and its impact on lung allograft inflammation
Assessment of pesticide safety knowledge and practices in Vietnam: a cross-sectional study of smallholder farmers in the Mekong delta (Publications)
Over the past three decades, the Vietnamese Mekong Delta experienced a significant increase in agricultural productivity, partly achieved through increased agrochemical use. To abate negative effects
Gender moderates results of a randomized clinical trial for the Khanya intervention for substance use and ART adherence in HIV care in South Africa (Publications)
Little is known about gender effects of alcohol and drug use (AOD) among people living with HIV (PLWH) in resource-limited settings. Using multilevel models, we tested whether gender moderated the eff
The impact of reactive case detection on malaria transmission in Zanzibar in the presence of human mobility (Publications)
Malaria persists at low levels on Zanzibar despite the use of vector control and case management. We use a metapopulation model to investigate the role of human mobility in malaria persistence on Zanz
Wastewater reveals the spatiotemporal spread of SARS-CoV-2 in the Canton of Ticino (Switzerland) during the onset of the COVID-19 pandemic (Publications)
Wastewater-based epidemiology (WBE) has emerged as an effective tool for monitoring SARS-CoV-2 dynamics during the COVID-19 pandemic. Here, we add a spatial component to WBE and use it to investigate
Genome-wide analyses identify <em>SCN5A</em> as a susceptibility locus for premature atrial contraction frequency (Publications)
Premature atrial contractions (PACs) are frequently observed on electrocardiograms and are associated with increased risks of atrial fibrillation (AF), stroke, and mortality. In this study, we aimed t
MEMO: mass spectrometry-based sample vectorization to explore chemodiverse datasets (Publications)
In natural products research, chemodiverse extracts coming from multiple organisms are explored for novel bioactive molecules, sometimes over extended periods. Samples are usually analyzed by liquid c
Spatial analysis of schistosomiasis in Hunan and Jiangxi provinces in the People's Republic of China (Publications)
Understanding the spatial distribution of schistosome infection is critical for tailoring preventive measures to control and eliminate schistosomiasis. This study used spatial analysis to determine ri