Evolution of drug resistance in tuberculosis: recent progress and implications for diagnosis and therapy (Publications)
Drug-resistant tuberculosis is a growing threat to global public health. Recent efforts to understand the evolution of drug resistance have shown that changes in drug-target interactions are only the
Activity of praziquantel enantiomers and main metabolites against <em>Schistosoma mansoni</em> (Publications)
A racemic mixture of R and S enantiomers of praziquantel (PZQ) is currently the treatment of choice against schistosomiasis. Though the S enantiomer and the metabolites are presumed to contribute only
IL-21 and IL-21R are not required for development of Th17 cells and autoimmunity in vivo (Publications)
Th17 cells have been recognized as the central effectors in organ-related autoimmune diseases. IL-6 is a key factor that reciprocally regulates Th17 and Foxp3(+) Treg differentiation by inhibition of
Crucial issues in think aloud techniques for cross cultural studies (Publications)
Implementing user-centered design (UCD) principles and conducting usability testing is especially critical in projects where developers do not originate from the deployed environment. However, traditi
A tradition and an epidemic: determinants of the campylobacteriosis winter peak in Switzerland (Publications)
Campylobacteriosis is the most frequently reported food borne infection in Switzerland. We investigated determinants of infections and illness experience in wintertime. A case-control study was conduc