Tuberculosis treatment outcomes among HIV/TB-coinfected children in the International Epidemiology Databases to Evaluate AIDS (IeDEA) network (Publications)
INTRODUCTION: Management of tuberculosis (TB) is challenging in HIV/TB-coinfected children. The World Health Organization recommends nucleic acid amplification tests for TB diagnosis, a 4-drug regimen
Hit-to-lead optimization of a novel class of potent, broad-spectrum trypanosomacides (Publications)
The parasitic trypanosomes Trypanosoma brucei and T. cruzi are responsible for significant human suffering in the form of human African trypanosomiasis (HAT) and Chagas disease. Drugs currently availa
Using the COMMVAC taxonomy to map vaccination communication interventions in Mozambique (Publications)
BACKGROUND: Improved communication about childhood vaccination is fundamental to increasing vaccine uptake in low-income countries. Mozambique, with 64% of children fully vaccinated, uses a range of c
Research on subgroups is not research on equity attributes: evidence from an overview of systematic reviews on vaccination (Publications)
BACKGROUND: Equity remains a priority in the international health development agenda. However, major inequities in vaccination coverage jeopardise the achievement of the Sustainable Development Goals.
Healthy lifestyle and heart rate variability in young adults (Publications)
BACKGROUND: We aimed to determine the association of a comprehensive healthy lifestyle with heart rate variability (HRV), a validated measure of autonomic function. DESIGN: This was a prospective coho
Spirometry reference equations for central European populations from school age to old age (Publications)
BACKGROUND: Spirometry reference values are important for the interpretation of spirometry results. Reference values should be updated regularly, derived from a population as similar to the population
40 years of progress in female cancer death risk: a Bayesian spatio-temporal mapping analysis in Switzerland (Publications)
BACKGROUND: In the past decades, mortality of female gender related cancers declined in Switzerland and other developed countries. Differences in the decrease and in spatial patterns within Switzerlan
Association between tuberculosis, diabetes and 25 hydroxyvitamin D in Tanzania: a longitudinal case control study (Publications)
BACKGROUND: Vitamin D level is inversely associated with tuberculosis (TB) and diabetes (DM). Vitamin D could be a mediator in the association between TB and DM. We examined the associations between v
Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation (Publications)
Lung function measures are used in the diagnosis of chronic obstructive pulmonary disease. In 38,199 European ancestry individuals, we studied genome-wide association of forced expiratory volume in 1