Discovery and optimization of a compound series active against <em>Trypanosoma cruzi</em>, the causative agent of chagas disease (Publications)
Chagas disease is caused by the protozoan parasite Trypanosoma cruzi. It is endemic in South and Central America and recently has been found in other parts of the world, due to migration of chronicall
Applied mathematical modelling to inform national malaria policies, strategies and operations in Tanzania (Publications)
BACKGROUND: More than ever, it is crucial to make the best use of existing country data, and analytical tools for developing malaria control strategies as the heterogeneity in malaria risk within coun
Recalibration and validation of the Swiss lichen bioindication methods for air quality assessment (Publications)
The aim of this study was to recalibrate the Swiss lichen bioindication methods, developed and calibrated with air pollution data 30 years ago. Since then, levels of air pollution have considerably de
Challenges in protocol development and interpretation of the Schistosomiasis Consortium for Operational Research and Evaluation intervention studies (Publications)
In 2010, the Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) began the design of randomized controlled trials to compare different strategies for praziquantel mass drug admi
Survive and thrive in Brazil: the Boa Vista Early Childhood program: study protocol of a stepped-wedge, randomized controlled trial (Publications)
BACKGROUND: A growing body of evidence suggests that early life health and developmental outcomes can be improved through parental support programs. The objective of this project was to test the feasi
Risk reduction of diarrhea and respiratory infections following a community health education program - a facility-based case-control study in rural... (Publications)
BACKGROUND: Diarrheal and acute respiratory infections remain a major cause of death in developing countries especially among children below 5 years of age. About 80% of all hospital attendances in Ke
Effects of transportation noise and particulate matter on the cardiovascular system: what is the new evidence? (Publications)
SUMMARY: Several decades of research provides compelling evidence that exposure to air pollution causes various diseases. Time series studies in Europe and the USA examined the short term effects on m
Prospective assessment of loss to follow-up: incidence and associated factors in a cohort of HIV-positive adults in rural Tanzania (Publications)
INTRODUCTION: Lifelong antiretroviral therapy (ART) improves health outcomes for HIV-positive individuals, but is jeopardized by irregular clinic attendance and hence poor adherence. Loss to follow-up
Where there is no hospital: improving the notification of community deaths (Publications)
BACKGROUND: Globally, an estimated two-thirds of all deaths occur in the community, the majority of which are not attended by a physician and remain unregistered. Identifying and registering these dea
Incidence trends of airflow obstruction among European adults without asthma: a 20-year cohort study (Publications)
Investigating COPD trends may help healthcare providers to forecast future disease burden. We estimated sex- and smoking-specific incidence trends of pre-bronchodilator airflow obstruction (AO) among