Randomized trial to improve children's body composition and micronutrient status among South African Children (Publications)
INTRODUCTION: Physical activity (PA) promotion combined with multi-micronutrient supplementation (MMNS) among school-age children may reduce fat mass accrual and increase muscle mass through different
Investigations of the metabolites of the trypanocidal drug melarsoprol (Publications)
BACKGROUND: Melarsoprol remains the first-choice drug for trypanosomiasis (human African sleeping sickness). To contribute to the sparse pharmacologic data and to better understand the cause of the fr
Efficacy and safety of albendazole plus ivermectin, albendazole plus mebendazole, albendazole plus oxantel pamoate, and mebendazole alone against... (Publications)
BACKGROUND: Existing anthelmintic drugs (eg, albendazole and mebendazole) have low efficacy against the intestinal nematode species Trichuris trichiura and the drug pipeline is exhausted. We aimed to
Repurposing of the open access malaria box for kinetoplastid diseases identifies novel active scaffolds against trypanosomatids (Publications)
Phenotypic screening had successfully been used for hit generation, especially in the field of neglected diseases, in which feeding the drug pipeline with new chemotypes remains a constant challenge.
Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for... (Publications)
BACKGROUND: Up-to-date evidence on levels and trends for age-sex-specific all-cause and cause-specific mortality is essential for the formation of global, regional, and national health policies. In th