Polyclonal gut colonization with extended-spectrum cephalosporin- and/or colistin-resistant Enterobacteriaceae: a normal status for hotel employees on... (Publications)
OBJECTIVES: For low-income countries, data regarding the intestinal colonization with extended-spectrum cephalosporin-resistant (ESC-R) and colistin-resistant (CST-R) Enterobacteriaceae in the communi
Ambient particulate air pollution and daily mortality in 652 cities (Publications)
BACKGROUND: The systematic evaluation of the results of time-series studies of air pollution is challenged by differences in model specification and publication bias. METHODS: We evaluated the associa
The HOSENG trial - effect of the provision of oral self-testing for absent and refusing individuals during a door-to-door HIV-testing campaign on... (Publications)
BACKGROUND: HIV-testing coverage remains below the targeted 90% despite efforts and resources invested. Home-based HIV-testing is a key approach endorsed by the World Health Organization (WHO), especi
Impact of the warm summer 2015 on emergency hospital admissions in Switzerland (Publications)
BACKGROUND: Only a few studies have examined the impact of a particular heat event on morbidity. The aim of this study was to evaluate the impact of the warm summer 2015 on emergency hospital admissio
Mechanistic dose-response modelling of animal challenge data shows that intact skin is a crucial barrier to leptospiral infection (Publications)
Leptospirosis is a widespread and potentially life-threatening zoonotic disease caused by spirochaetes of the genus Leptospira. Humans become infected primarily via contact with environmental reservoi
Targeting a large active site: structure-based design of nanomolar inhibitors of <em>Trypanosoma brucei </em>trypanothione reductase (Publications)
Trypanothione reductase (TR) plays a key role in the unique redox metabolism of trypanosomatids, the causative agents of human African trypanosomiasis (HAT), Chagas' disease, and leishmaniases. Introd
Five-year impact of different multi-year mass drug administration strategies on childhood <em>Schistosoma mansoni</em>-associated morbidity: a... (Publications)
The WHO recommends mass treatment with praziquantel as the primary approach for Schistosoma mansoni-related morbidity control in endemic populations. The Schistosomiasis Consortium for Operational Res