Effectiveness of a home-based counselling strategy on neonatal care and survival: a cluster-randomised trial in six districts of rural southern... (Publications)
BACKGROUND: We report a cluster-randomised trial of a home-based counselling strategy, designed for large-scale implementation, in a population of 1.2 million people in rural southern Tanzania. We hyp
Local cellular immune responses and pathogenesis of Buruli ulcer lesions in the experimental <em>Mycobacterium ulcerans</em> pig infection model (Publications)
BACKGROUND: Buruli ulcer is a neglected tropical disease of the skin that is caused by infection with Mycobacterium ulcerans. We recently established an experimental pig (Sus scrofa) infection model f
Local heat application for the treatment of Buruli ulcer: results of a phase II open label single center non comparative clinical trial (Publications)
BACKGROUND: Buruli ulcer (BU) is a necrotising skin disease most prevalent among West African children. The causative organism, Mycobacterium ulcerans, is sensitive to temperatures above 37 degrees C.
Travellers' profile, travel patterns and vaccine practices - a 10-year prospective study in a Swiss Travel Clinic (Publications)
BACKGROUND: The travel clinic in Lausanne serves a catchment area of 700 000 of inhabitants and provides pre- and post-travel consultations. This study describes the profile of attendees before depart
Changes in malaria burden and transmission in sentinel sites after the roll-out of long-lasting insecticidal nets in Papua New Guinea (Publications)
BACKGROUND: Papua New Guinea exhibits a complex malaria epidemiology due to diversity in malaria parasites, mosquito vectors, human hosts, and their natural environment. Heterogeneities in transmissio
Long-term air pollution and traffic noise exposures and mild cognitive impairment in older adults: a cross-sectional analysis of the Heinz Nixdorf... (Publications)
BACKGROUND: Mild cognitive impairment (MCI) describes the intermediate state between normal cognitive aging and dementia. Adverse effects of air pollution (AP) on cognitive functions have been propose
Spatial distribution of <em>Mycobacterium ulcerans</em> in Buruli ulcer lesions: implications for laboratory diagnosis (Publications)
BACKGROUND: Current laboratory diagnosis of Buruli ulcer (BU) is based on microscopic detection of acid fast bacilli, quantitative real-time PCR (qPCR), histopathology or cultivation. Insertion sequen
Wayanin and guaijaverin, two active metabolites found in a <em>Psidium acutangulum</em> Mart. ex DC (syn. P. persoonii McVaugh) (Myrtaceae)... (Publications)
ETHNOPHARMACOLOGICAL RELEVANCE: Psidium acutangulum Mart. ex DC is a small tree used by the Wayana Amerindians from the Upper-Maroni in French Guiana for the treatment of malaria. AIM OF THE STUDY: In