Aquaporin 2 mutations in <em>Trypanosoma brucei gambiense</em> field isolates correlate with decreased susceptibility to pentamidine and melarsoprol (Publications)
The predominant mechanism of drug resistance in African trypanosomes is decreased drug uptake due to loss-of-function mutations in the genes for the transporters that mediate drug import. The role of
Use of antibiotics within the IMCI guidelines in outpatient settings in Papua New Guinean children: an observational and effectiveness study (Publications)
INTRODUCTION: There is a need to investigate the effectiveness and appropriateness of antibiotics prescription within the Integrated Management of Childhood Illness (IMCI) strategy in the context of r
Long-term dominance of <em>Mycobacterium tuberculosis</em> Uganda family in peri-urban Kampala-Uganda is not associated with cavitary disease (Publications)
BACKGROUND: Previous studies have shown that Mycobacterium tuberculosis (MTB) Uganda family, a sub-lineage of the MTB Lineage 4, is the main cause of tuberculosis (TB) in Uganda. Using a well characte
Tuberculosis in antiretroviral treatment programs in lower income countries: availability and use of diagnostics and screening (Publications)
OBJECTIVES: In resource-constrained settings, tuberculosis (TB) is a common opportunistic infection and cause of death in HIV-infected persons. TB may be present at the start of antiretroviral therapy