Risk factors associated with the epilepsy treatment gap in Kilifi, Kenya: a cross-sectional study (Publications)
BACKGROUND: Many people with epilepsy in low-income countries do not receive appropriate biomedical treatment. This epilepsy treatment gap might be caused by patients not seeking biomedical treatment
Behavior of sunbed users in Switzerland (Publications)
OBJECTIVES: A constant rise in the number of skin cancer cases has been observed during the last few years. An important reason for this trend is that exposure of the population to UV radiation is hig
First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials (Publications)
AIMS: To asses the safety and pharmacokinetics of a new synthetic ozonide antimalarial, OZ439, in a first-in-man, double-blind study in healthy volunteers. METHODS: OZ439 was administered as single or
Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and... (Publications)
Previous studies have identified the 3,6-dialkyl-4-hydroxy-pyran-2-one marine microbial metabolites pseudopyronines A and B to be modest growth inhibitors of Mycobacterium tuberculosis and a range of
Design, synthesis and evaluation of novel uracil acetamide derivatives as potential inhibitors of <em>Plasmodium falciparum</em> dUTP... (Publications)
The ubiquitous enzyme dUTP nucleotidohydrolase (dUTPase) catalyses the hydrolysis of dUTP to dUMP and can be considered as the first line of defence against incorporation of uracil into DNA. Inhibitio
Relationship of atmospheric pollution characterized by gas NO2 and particles (PM10) to microbial communities living in bryophytes at three differently... (Publications)
Atmospheric pollution has become a major problem for modern societies owing to its fatal effects on both human health and ecosystems. We studied the relationships of nitrogen dioxide atmospheric pollu
Association of cytokeratin 7 and 19 expression with genomic stability and favorable prognosis in clear cell renal cell cancer (Publications)
The purpose of our study was to demonstrate that distinct cytogenetic alterations in the most common subtype of renal cell cancer, clear cell renal cell carcinoma (ccRCC), are reflected in protein exp
Efficacy of the novel diamidine compound 2,5-Bis(4-amidinophenyl)- furan-bis-<em>O</em>-Methlylamidoxime (Pafuramidine, DB289) against <em>Trypanosoma... (Publications)
Owing to the lack of oral drugs for human African trypanosomiasis, patients have to be hospitalized for 10 to 30 days to facilitate treatment with parenterally administered medicines. The efficacy of
Urban agricultural land use and characterization of mosquito larval habitats in a medium-sized town of Côte d'Ivoire (Publications)
Urban agriculture is common across Africa and contributes to the livelihoods of urban dwellers. Some crop systems create suitable mosquito breeding sites and thus might affect malaria transmission. Th