Age-shifting in malaria incidence as a result of induced immunological deficit: a simulation study (Publications)
Effective population-level interventions against Plasmodium falciparum malaria lead to age-shifts, delayed morbidity or rebounds in morbidity and mortality whenever they are deployed in ways that do n
'I know it has worked for millions of years': the role of the 'natural' in parental reasoning against child immunization in a qualitative study in... (Publications)
BACKGROUND: Despite efforts of international and national health authorities, immunization coverage and timeliness of vaccination against dangerous childhood diseases have been adversely affected by p
Use of recombinant virus replicon particles for vaccination against <em>Mycobacterium ulcerans</em> disease (Publications)
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries. The maj
Direct sequencing of Legionella pneumophila from respiratory samples for sequence-based typing analysis (Publications)
We have developed a procedure to test the efficiency and reliability of sequencing of Legionella pneumophila genes directly from respiratory samples and have compared the results with those derived fr
Biomarkers of host response predict primary end-point radiological pneumonia in Tanzanian children with clinical pneumonia: a prospective cohort study (Publications)
BACKGROUND: Diagnosing pediatric pneumonia is challenging in low-resource settings. The World Health Organization (WHO) has defined primary end-point radiological pneumonia for use in epidemiological
Bayesian geostatistical model-based estimates of soil-transmitted helminth infection in Nigeria, including annual deworming requirements (Publications)
BACKGROUND: The acceleration of the control of soil-transmitted helminth (STH) infections in Nigeria, emphasizing preventive chemotherapy, has become imperative in light of the global fight against ne
Spatial variation and land use regression modeling of the oxidative potential of fine particles (Publications)
BACKGROUND: Oxidative potential (OP) has been suggested to be a more health-relevant metric than particulate matter (PM) mass. Land use regression (LUR) models can estimate long-term exposure to air p
Distribution of malaria exposure in endemic countries in Africa considering country levels of effective treatment (Publications)
BACKGROUND: Malaria prevalence, clinical incidence, treatment, and transmission rates are dynamically interrelated. Prevalence is often considered a measure of malaria transmission, but treatment of c