Immunoglobulin G subclass-specific responses against <em>Plasmodium falciparum</em> merozoite antigens are associated with control of parasitemia and... (Publications)
Substantial evidence indicates that antibodies to Plasmodium falciparum merozoite antigens play a role in protection from malaria, although the precise targets and mechanisms mediating immunity remain
Chronic bronchitis and urban air pollution in an international study (Publications)
Objectives The chronic effects of urban air pollution are not well known. Our aim was to investigate the association between the prevalence and new onset of chronic bronchitis and urban air pollution.
Continuous video-EEG monitoring increases detection rate of nonconvulsive status epilepticus in the ICU (Publications)
Purpose: Status epilepticus (SE) is an important neurologic emergency requiring treatment on an intensive care unit (ICU). Although convulsive SE is self-evident, the diagnosis of nonconvulsive SE (NC
Acute phase proteins and white blood cell levels for prediction of infectious complications in status epilepticus (Publications)
ABSTRACT: INTRODUCTION: Infections in status epilepticus (SE) patients result in severe morbidity making early diagnosis crucial. As SE may lead to inflammatory reaction, the value of acute phase prot
Genesis of and trafficking to the Maurer's clefts of <em>Plasmodium falciparum</em>-infected erythrocytes (Publications)
Malaria parasites export proteins beyond their own plasma membrane to locations in the red blood cells in which they reside. Maurer's clefts are parasite-derived structures within the host cell cytopl
Socio-cultural determinants of anticipated acceptance of an oral cholera vaccine in western Kenya (Publications)
SUMMARYDeterminants of anticipated acceptance of an oral cholera vaccine (OCV) were studied in urban and rural communities of Western Kenya. An explanatory model interview administered to 379 communit
Compounds structurally related to ellagic acid show improved antiplasmodial activity (Publications)
The cancer chemopreventive agent ellagic acid (EA) is a known inhibitor of glutathione S-transferases (GSTs) and possesses antiplasmodial activities in the upper-nanomolar range. In the recent drug de
Single nucleotide polymorphisms in <em>Mycobacterium tuberculosis</em> and the need for a curated database (Publications)
Recent advances in DNA sequencing have led to the discovery of thousands of single nucleotide polymorphisms (SNPs) in clinical isolates of Mycobacterium tuberculosis complex (MTBC). This genetic varia
Interaction of monobenzamidine-linked trypanocides with the <em>Trypanosoma brucei</em> P2 aminopurine transporter (Publications)
Single benzamidine group-carrying compounds were shown to interact with the Trypanosoma brucei P2 aminopurine transporter. Replacement of the amidine with a guanidine group decreased affinity. Trypano