Changing from whole-cell to acellular pertussis vaccines would trade superior tolerability for inferior protection (Publications)
Notifications of infant deaths, assumed to be related to the introduction of new pentavalent DTwP-Hib-HBV childhood vaccines, caused, during 2008-2010 in few Asian countries, temporary interruptions o
Defining the relationship between infection prevalence and clinical incidence of<em> Plasmodium falciparum</em> malaria (Publications)
In many countries health system data remain too weak to accurately enumerate Plasmodium falciparum malaria cases. In response, cartographic approaches have been developed that link maps of infection p
International scale implementation of the CNOSSOS-EU road traffic noise predictin model for epidemiological studies (Publications)
The EU-FP7-funded BioSHaRE project is using individual-level data pooled from several national cohort studies in Europe to investigate the relationship of road traffic noise and health. The detailed i
Spatial distribution of schistosomiasis and treatment needs in sub-Saharan Africa: a systematic review and geostatistical analysis (Publications)
BACKGROUND: Schistosomiasis affects more than 200 million individuals, mostly in sub-Saharan Africa, but empirical estimates of the disease burden in this region are unavailable. We used geostatistica
Quantifying the health impacts of ambient air pollutants: recommendations of a WHO/Europe project (Publications)
OBJECTIVE: Quantitative estimates of air pollution health impacts have become an increasingly critical input to policy decisions. The WHO project "Health risks of air pollution in Europe-HRAPIE" was i
"Pseudo-Beijing": evidence for convergent evolution in the direct repeat region of <em>Mycobacterium tuberculosis</em> (Publications)
BACKGROUND: Mycobacterium tuberculosis has a global population structure consisting of six main phylogenetic lineages associated with specific geographic regions and human populations. One particular
The activities of current antimalarial drugs on the life cycle stages of <em>Plasmodium</em>: a comparative study with human and rodent parasites (Publications)
BACKGROUND: Malaria remains a disease of devastating global impact, killing more than 800,000 people every year-the vast majority being children under the age of 5. While effective therapies are avail
Modelling the cost-effectiveness of mass screening and treatment for reducing <em>Plasmodium falciparum</em> malaria burden (Publications)
BACKGROUND: Past experience and modelling suggest that, in most cases, mass treatment strategies are not likely to succeed in interrupting Plasmodium falciparum malaria transmission. However, this doe