Malaria control across borders: quasi-experimental evidence from the Trans-Kunene malaria initiative (TKMI) (Publications)
BACKGROUND: The transmission of malaria through population inflows from highly endemic areas with limited control efforts poses major challenges for national malaria control programmes. Several multilateral [...] l efforts. CONCLUSIONS: The impact of malaria programmes depends on programme efforts in surrounding areas with differential control efforts. Coordinated malaria programming within and across countries [...] the potential impact of such a programme at the Angolan-Namibian border....
Whole blood transcriptome changes following controlled human malaria infection in malaria pre-exposed volunteers correlate with parasite prepatent... (Publications)
Malaria continues to be one of mankind's most devastating diseases despite the many and varied efforts to combat it. Indispensable for malaria elimination and eventual eradication is the development of [...] of effective vaccines. Controlled human malaria infection (CHMI) is an invaluable tool for vaccine efficacy assessment and investigation of early immunological and molecular responses against Plasmodium [...] cell cycle, phosphatidylinositol signaling and erythrocyte development. Our study...
Assessment of ultra-sensitive malaria diagnosis versus standard molecular diagnostics for malaria elimination: an in-depth molecular community... (Publications)
BACKGROUND: Submicroscopic malaria infections contribute to transmission in exposed populations but their extent is underestimated even by standard molecular diagnostics. Sophisticated sampling and ul [...] sensitive methods with the aim to understand what diagnostic sensitivity is necessary to guide malaria interventions. METHODS: Venous blood samples were collected from participants in a cross-sectional
Fake malaria and hidden parasites - the ambiguity of malaria (Publications)
and education, programmes, and as a result, biomedical knowledge on malaria is comparatively high. However the cultural model of malaria does not always explain all the events that occur during an actual [...] Lay perspectives and health-seeking behaviour for malaria were investigated in an ethnographic study carried out in a village in south-eastern Tanzania. The inhabitants have easy access to hospital services [...] or the symptoms persist despite antimalarial treatment. Under these...
Malaria standby emergency treatment (SBET) for travelers visiting malaria endemic areas: a systematic review and meta-analysis (Publications)
Malaria prevention methods for travelers to low or moderate malaria risk areas varies and remains controversial. Standby Emergency Treatment (SBET) for malaria is one possible strategy increasingly recommended [...] proportion carrying SBET, the response to fever (use of SBET, health facility attendance, use of malaria rapid diagnostic test [mRDT]), adverse events to SBET, and the proportion using SBET incorrectly [...] current SBET strategy should be considered, such as better selection of...
Malaria-anemia comorbidity prevalence as a measure of malaria-related deaths in sub-Saharan Africa (Publications)
association of malaria parasitaemia, anemia, and malariaanemia comorbidity with all-cause under-five mortality and evaluated the potential of malaria-anemia comorbidity prevalence to quantify malaria-related [...] utilized to determine the relationship between malaria and mortality in endemic countries. Most of these efforts have focused on deaths directly attributed to malaria, while they overlooked causes of mortality [...] Mortality hazard obtained from malaria-anemia comorbidity prevalence...
Trends in reported malaria cases and the effects of malaria control in the Democratic Republic of the Congo (Publications)
upscaling of malaria control efforts have taken place over the last 15 years in the Democratic Republic of Congo, the country with the second highest malaria case load after Nigeria. Malaria control int [...] Goals. We analysed the effects of these interventions on malaria cases at health facility level, using a retrospective trend analysis of malaria cases between 2005 and 2014. Data were collected from outpatient [...] represents all eco-epidemiological malaria settings across the country....
Science of Eradication: Malaria (Courses)
Eradication: Malaria Core Course is an intensive weeklong foundational leadership development course that provides participants with a multidisciplinary perspective on approaches to malaria elimination