Tolerability and efficacy of a pediatric granule formulation of artesunate-mefloquine in young children from Cameroon with uncomplicated falciparum... (Publications)
developed. In this open, non-comparative study in Cameroonian children with uncomplicated falciparum malaria, the safety and efficacy of this formulation was tested, with a particular emphasis on the risk of
<em>Falciparum </em>malaria presenting with pruritic rashes (Publications)
Rash is not generally believed to be a symptom of malaria. Two cases of acute falciparum malaria in non-immune residents of Mozambique who presented with pruritic rashes are reported. One case exhibited [...] Review of the literature reveals cases of malaria from India, East Africa, France, and the USA presenting with urticaria or a pruritic rash. Previous exposure to malaria may be a factor in these presentations [...] ns. Physicians should not discount the diagnosis of malaria in patients with...
Prospective risk of morbidity in relation to malaria infection in an area of high endemicity of multiple species of <em>Plasmodium</em> (Publications)
Plasmodium malariae (13.8%), cross-sectional analysis found P. falciparum infection to be independent of the other species despite heterogeneities in transmission. Plasmodium vivax and P. malariae infections [...] health-center morbidity supported the idea that P. malariae infection protects against disease, but indicated greater protection against non-malaria than P. falciparum- associated fevers. Plasmodium vivax [...] infections were negatively correlated. Plasmodium malariae infection was...
Cytochrome P450 6M2 from the malaria vector <em>Anopheles gambiae</em> metabolizes pyrethroids: sequential metabolism of deltamethrin revealed (Publications)
Resistance to pyrethroid insecticides in the malaria vector Anopheles gambiae is a major threat to malaria control programmes. Cytochome P450-mediated detoxification is an important resistance mechanism [...] metabolic resistance to pyrethroids and thus an important target for the design of new tools to combat malaria
In a randomized controlled trial of iron fortification, anthelmintic treatment, and intermittent preventive treatment of malaria for anemia control in... (Publications)
bioavailability of dietary iron, malaria, and helminth infection. In this study, we aimed to assess the effect of iron fortification, intermittent preventive treatment (IPT) of malaria, and anthelmintic treatment