Jonathan L. Vennerstrom: I was standing on the shoulders of giants (Publications)
collaborations with the Swiss Tropical and Public Health Institute (Swiss TPH) and the Medicines for Malaria Venture (MMV) have paved the way for antimalarial and antischistosomal drugs. In recognition of his
Incorporation of an intramolecular hydrogen bonding motif in the side chain of antimalarial benzimidazoles (Publications)
activity against chloroquine-sensitive (NF54) and multi-drug resistant (K1) strains of the human malaria parasite Plasmodium falciparum. Compounds were also screened for their cytotoxicity towards a mammalian
Safety of artemether-lumefantrine exposure in first trimester of pregnancy: an observational cohort (Publications)
s in early pregnancy. They are, therefore, not recommended by WHO as a first-line treatment for malaria in first trimester due to associated embryo-foetal toxicity in animal studies. The study assessed
New 4-amino-2-azabicyclo[3.2.2]nonane derivatives and their antiprotozoal potencies (Publications)
East African sleeping sickness, Trypanosoma b. rhodesiense, and a protozoan parasite which causes Malaria tropica, Plasmodium falciparum K-1, a strain which is resistant to chloroquine and pyrimethamine
Inhibitors of Plasmepsin II-potential antimalarial agents (Publications)
In order to overcome the problem of drug resistance in malaria, it appears wise to concentrate drug discovery efforts toward new structural classes and new mechanisms of action. We report our results,
Long-lasting and fast-acting<em> in vivo</em> efficacious antiplasmodial azepanylcarbazole amino alcohol (Publications)
With approximately 429,000 deaths in 2016, malaria remains a major infectious disease where the need to treat the fever symptoms, but also to provide relevant post-treatment prophylaxis, is of major importance
Ownership and usage of mosquito nets after four years of large-scale free distribution in Papua New Guinea (Publications)
Guinea (PNG) is a highly malaria endemic country in the South-West Pacific with a population of approximately 6.6 million (2009). In 2004, the country intensified its malaria control activities with support
Interactions and potential implications of <em>Plasmodium falciparum</em>-hookworm coinfection in different age groups in south-central Côte... (Publications)
these parasitic infections is of public health relevance considering that control measures targeting malaria and helminthiases are going to scale.METHODOLOGY: A cross-sectional survey was carried out in April [...] information could have important implications when implementing integrated control measures against malaria and helminthiases.
Strategies for detection of <em>Plasmodium species</em> gametocytes (Publications)
transmission stages of malaria parasites, are determined for predicting the infectiousness of humans to mosquitoes. This measure is used for evaluating interventions that aim at reducing malaria transmission.
Mass distribution of free insecticide-treated nets do not interfere with continuous net distribution in Tanzania (Publications)
BACKGROUND: To protect the most vulnerable groups from malaria (pregnant women and infants) the Tanzanian Government introduced a subsidy (voucher) scheme in 2004, on the basis of a public-private partnership [...] for the continuation of this effort in Tanzania and for emulation by other countries with endemic malaria