Malaria case management in Papua New Guinea prior to the introduction of a revised treatment protocol (Publications)
document malaria case management practices in Papua New Guinea prior to the introduction of a revised national malaria treatment protocol. The revised protocol stipulates routine testing of malaria infection [...] observation instrument. RESULTS: Overall, 15% of observed fever patients (n=468) were tested for malaria infection by rapid diagnostic test and a further 3.6% were tested via microscopy. An anti-malarial [...] what they might look like were discussed in only 1.1% of cases. CONCLUSION:...
Transmission of malaria in relation to distribution and coverage of long-lasting insecticidal nets in central Côte d'Ivoire (Publications)
BACKGROUND: The use of long-lasting insecticidal nets (LLINs) is an effective malaria control strategy. However, there are challenges to achieve high coverage, such as distribution sustainability, and [...] study assessed the effect of LLINs coverage and contextual factors on entomological indicators of malaria in rural Côte d'Ivoire. METHODS: The study was carried out between July 2009 and May 2012 in three [...] of central Côte d'Ivoire. In Bozi and Yoho, LLINs were distributed free of charge...
Improving health worker adherence to malaria treatment guidelines in Papua New Guinea: feasibility and acceptability of a text message reminder... (Publications)
whether a text message reminder service designed to support health worker adherence to a revised malaria treatment protocol is feasible and acceptable in Papua New Guinea (PNG). The study took place in [...] resources. In conclusion, a text message reminder service to support health worker adherence to the new malaria treatment protocol is feasible and acceptable in PNG. A rigorous pragmatic, effectiveness trial would
Potential causes and consequences of behavioural resilience and resistance in malaria vector populations: a mathematical modelling analysis (Publications)
evade fatal exposure to insecticidal nets and sprays represents the primary obstacle to eliminating malaria. However, it remains unclear which behaviours are most important for buffering mosquito and parasite
Community response to intermittent preventive treatment of malaria in infants (IPTi) in Papua New Guinea (Publications)
Africa this article aims to investigate the acceptability of intermittent preventive treatment of malaria in infants (IPTi) in Papua New Guinea (PNG). METHODS: A questionnaire was administered to mothers [...] is little evidence that IPTi has negative impacts on attitudes to EPI, EPI adherence or existing malaria prevention practices. CONCLUSION: The degree of similarity between findings from the acceptability [...] health cultures, appears to be accepted easily and has little impact on...
Naturally acquired immune responses to <em>P. vivax</em> merozoite surface protein 3alpha and merozoite surface protein 9 are associated with reduced... (Publications)
is the most geographically widespread human malaria parasite. Cohort studies in Papua New Guinea have identified a rapid onset of immunity against vivax-malaria in children living in highly endemic areas [...] and Merozoite Surface Protein 9 (PvMSP9) were measured and related to prospective risk of P. vivax malaria during 16 months of active follow-up. Overall, there was a low prevalence of antibodies to PvMSP3alpha [...] PvMSP9 N-terminus (aIRR = 0.68, p = 0.035) were associated with protection...
Seeking treatment for symptomatic malaria in Papua New Guinea (Publications)
reported suffering from malaria in the previous four weeks. A probit model was then used to identify the factors determining whether or not people sought treatment for presumptive malaria. Multinomial logit [...] BACKGROUND: Malaria places a significant burden on the limited resources of many low income countries. Knowing more about why and where people seek treatment will enable policy makers to better allocate [...] resources. This study aims to better understand what influences...
Malaria Policy Advisory Committee to the WHO: conclusions and recommendations of March 2013 meeting (Publications)
resource allocation for malaria control; malaria surveillance and the need for a surveillance, monitoring and evaluation Technical Expert Group; criteria and classification related to malaria elimination; the [...] Suriname; the outcomes from a consultation on non-malaria febrile illness; the outcomes from the second meeting of the Evidence Review Group on malaria burden estimation; an update on the review of the [...] Guidelines for the Treatment of Malaria; an update regarding progress on the...
Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite <em>Plasmodium falciparum</em> (Publications)
BACKGROUND: The post-genomic era of malaria research provided unprecedented insights into the biology of Plasmodium parasites. Due to the large evolutionary distance to model eukaryotes, however, we lack [...] serve as an important platform for dissecting general and parasite-specific nuclear processes in malaria parasites. Moreover, as the first nuclear proteome characterized in any protist organism, it will
Health worker factors associated with prescribing of artemisinin combination therapy for uncomplicated malaria in rural Tanzania (Publications)
uncomplicated malaria defined as prescription of artemisinin-based combination therapy (ACT) for patients with fever and Plasmodium falciparum asexual infection based on blood slide or malaria rapid diagnostic [...] patients with uncomplicated malaria who were seen in a health facility with ACT in stock, and 71 health workers practicing in 30 health facilities. Overall, 58% of malaria patients were correctly treated [...] with correct ACT prescription for uncomplicated malaria. Targeted...