Effective coverage and systems effectiveness for malaria case management in sub-Saharan African countries (Publications)
Scale-up of malaria preventive and control interventions over the last decade resulted in substantial declines in mortality and morbidity from the disease in sub-Saharan Africa and many other parts of [...] infectious reservoir and averting emergence and spread of drug resistance. However many patients with malaria do not access care, providers do not comply with treatment guidelines, and hence, patients do not [...] seeking, provider compliance, adherence, and quality of medication to estimate...
An operational comparative study of quinine and artesunate for the treatment of severe malaria in hospitals and health centres in the Democratic... (Publications)
has the highest number of severe malaria cases in the world. In early 2012, the National Malaria Control Programme (NMCP) changed the policy for treating severe malaria in children and adults from injectable
Managing the sick child in the era of declining malaria transmission: development of ALMANACH, an electronic algorithm for appropriate use of... (Publications)
based on a respiratory rate threshold of 50 assessed twice for febrile children 12-59 months; iv) malaria rapid diagnostic test performed for all febrile children. In the absence of identified source of
The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient... (Publications)
d Plasmodium falciparum malaria in Africa. We investigated the impact of different dosing strategies on the efficacy of this combination for the treatment of falciparum malaria. METHODS: Individual patient
Safety and efficacy of the RTS,S/AS01(E) candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a... (Publications)
0012) against first malaria episodes and 59% (36-74; p=0.0001) against all malaria episodes. For the entire study period, (total vaccinated cohort) vaccine efficacy against all malaria episodes was higher [...] BACKGROUND: The RTS,S/AS01(E) candidate malaria vaccine is being developed for immunisation of infants in Africa through the expanded programme on immunisation (EPI). 8 month follow-up data have been reported [...] did a randomised, open-label, phase 2 trial of safety and efficacy of the...