Estimation of malaria-attributable fever in malaria test-positive febrile outpatients in three provinces of Mozambique, 2018 (Publications)
estimate the proportion of malaria-attributable fevers in malaria test-positive febrile patients. Depending on the antigen, estimated rates of malaria-attributable fever in malaria test-positive febrile patients [...] Like most malaria-endemic countries, Mozambique relies on tabulation of confirmed malaria test-positive febrile patients to track incidence of malaria. However, this approach is potentially biased by [...] indicate that most malaria test-positive febrile patients in the three...
Correction to: Malaria control across borders: quasi-experimental evidence from the Trans-Kunene malaria initiative (TKMI) (Publications)
Following publication of the original article [1], the authors flagged an error in Addition file 6.
Child health and infection with low density (CHILD) malaria: a protocol for a randomised controlled trial to assess the long-term health and... (Publications)
participants receive malaria testing using RDT and qPCR three times annually, and malaria testing by RDT only when presenting with fever. PCDm and PCD participants receive malaria testing by RDT and qPCR [...] INTRODUCTION: As malaria declines, low-density malaria infections (LMIs) represent an increasing proportion of infections and may have negative impacts on child health and cognition, necessitating development [...] respectively, when presenting with fever. RDT or qPCR positive...
Dihydroartemisinin-piperaquine effectiveness for seasonal malaria chemoprevention in settings with extended seasonal malaria transmission in Tanzania (Publications)
course of DP for three consecutive months regardless of malaria infection status, and those in the control clusters received no intervention. Malaria infection was assessed at before the first-round and at [...] Effectiveness of dihydroartemisinin-piperaquine (DP) as seasonal malaria chemoprevention (SMC) was assessed in Nanyumbu and Masasi Districts. Between March and June 2021, children aged 3-59 months were [...] at 7 weeks after the third-round of DP in both arms. Malaria prevalence after...
Effectiveness of intermittent preventive treatment with sulfadoxine-pyrimethamine during pregnancy on placental malaria, maternal anaemia and... (Publications)
areas with different malaria transmission intensities. METHODS: Prospective observational study recruiting pregnant women in two health facilities in areas with high and low malaria transmission intensities [...] risk factors for placental malaria (OR 2.4; CI 1.1-5.0; P = 0.025) and (OR 9.4; CI 3.2-27.7; P < 0.001), respectively. IPTp was associated with a lower risk of placental malaria (OR 0.3; CI 0.1-1.0; P = [...] the low transmission area to prevent one case of placental malaria....
Malaria control across borders: quasi-experimental evidence from the Trans-Kunene malaria initiative (TKMI) (Publications)
BACKGROUND: The transmission of malaria through population inflows from highly endemic areas with limited control efforts poses major challenges for national malaria control programmes. Several multilateral [...] l efforts. CONCLUSIONS: The impact of malaria programmes depends on programme efforts in surrounding areas with differential control efforts. Coordinated malaria programming within and across countries [...] the potential impact of such a programme at the Angolan-Namibian border....
Whole blood transcriptome changes following controlled human malaria infection in malaria pre-exposed volunteers correlate with parasite prepatent... (Publications)
Malaria continues to be one of mankind's most devastating diseases despite the many and varied efforts to combat it. Indispensable for malaria elimination and eventual eradication is the development of [...] of effective vaccines. Controlled human malaria infection (CHMI) is an invaluable tool for vaccine efficacy assessment and investigation of early immunological and molecular responses against Plasmodium [...] cell cycle, phosphatidylinositol signaling and erythrocyte development. Our study...
Malaria standby emergency treatment (SBET) for travelers visiting malaria endemic areas: a systematic review and meta-analysis (Publications)
Malaria prevention methods for travelers to low or moderate malaria risk areas varies and remains controversial. Standby Emergency Treatment (SBET) for malaria is one possible strategy increasingly recommended [...] proportion carrying SBET, the response to fever (use of SBET, health facility attendance, use of malaria rapid diagnostic test [mRDT]), adverse events to SBET, and the proportion using SBET incorrectly [...] current SBET strategy should be considered, such as better selection of...