Identification of new human malaria parasite <em>Plasmodium falciparum</em> dihydroorotate dehydrogenase inhibitors by pharmacophore and... (Publications)
Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH), a key enzyme in the de novo pyrimidine biosynthesis pathway, which the Plasmodium falciparum relies on exclusively for survival, has emerg
Policy analysis for deciding on a malaria vaccine RTS,S in Tanzania (Publications)
BACKGROUND: Traditionally, it has taken decades to introduce new interventions in low-income countries. Several factors account for these delays, one of which is the absence of a framework to facilita
Bimodal X-ray and infrared imaging of an organometallic derivative of praziquantel in <em>Schistosoma mansoni</em> (Publications)
An organometallic derivative of praziquantel was studied directly in worms, using ICP-MS for quantification and synchrotron based imaging. X-Ray fluorescence and IR absorption microspectroscopy, were
Reaching the surveillance-response stage of schistosomiasis control in the People's Republic of China: a modelling approach (Publications)
With the goal set to eliminate schistosomiasis nationwide by 2020, The People's Republic of China has initiated the surveillance-response stage to identify remaining sources of infection and potential
Synthesis of novel amide and urea derivatives of thiszol-2-ethylamines and their activity against<em> Trypanosoma brucei rhodesiense</em> (Publications)
2-(2-Benzamido)ethyl-4-phenylthiazole (1) was one of 1035 molecules (grouped into 115 distinct scaffolds) found to be inhibitory to Trypanosoma brucei, the pathogen causing human African trypanosomias
Prenatal exposure to NO2 and ultrasound measures of fetal growth in the Spanish INMA cohort (Publications)
BACKGROUND: Air pollution exposure during pregnancy has been associated with impaired fetal growth. However, few studies have measured fetal biometry longitudinally, remaining unclear as to whether th
Operational strategies of anti-malarial drug campaigns for malaria elimination in Zambia's southern province: a simulation study (Publications)
BACKGROUND: Malaria elimination requires reducing both the potential of mosquitoes to transmit parasites to humans and humans to transmit parasites to mosquitoes. To achieve this goal in Southern prov
Utilization of health care services among internal migrants in Hanoi and its correlation with health insurance: a cross-sectional study (Publications)
BACKGROUND: Economic transition (DoiMoi) in the 1980s in Viet Nam has led to internal migration, particularly rural-to-urban migration. Many studies suggested that there is a difference between non-mi
Electroencephalographic features of convulsive epilepsy in Africa: a multicentre study of prevalence, pattern and associated factors (Publications)
OBJECTIVE: We investigated the prevalence and pattern of electroencephalographic (EEG) features of epilepsy and the associated factors in Africans with active convulsive epilepsy (ACE). METHODS: We ch