Pyrocoll, an antibiotic, antiparasitic and antitumor compound produced by a novel alkaliphilic streptomyces strain (Publications)
A new secondary metabolite was detected in the culture extract of Streptomyces sp. AK 409 by HPLC-diode-array screening. The metabolite was identified as pyrocoll, which is known to be a constituent o
Disesquiterpene and sesquiterpene coumarins from <em>Ferula pseudalliacea</em>, and determination of their absolute configurations (Publications)
The first disesquiterpene coumarin, sanandajin, five sesquiterpene coumarins, kamolonol acetate, fekrynol acetate, ethyl galbanate, methyl galbanate, farnesiferol B, and a sesquiterpene, aristolone, w
Sexual compatibility among <em>Trypanosoma brucei</em> isolates from an epidemic area in southeastern Uganda (Publications)
For the first time, two clones of Trypanosoma brucei from the same epidemic area in southeastern Uganda were successfully crossed. The cotransmission experiments were as close to natural conditions as
Antiprotozoal activity of 1-phenethyl-4-aminopiperidine derivatives (Publications)
A series of 44 4-aminopiperidine derivatives was screened in vitro against four protozoan parasites (Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani, and Plasmodium falciparum).
Molecular approaches to epidemiology and clinical aspects of malaria (Publications)
Malaria is a problem of global importance, responsible for 1-2 million deaths per year, mainly in African children, as well as considerable morbidity manifested as severe anaemia and encephalopathy in