Identification and qualification of a new family of peptide endocannabinoids (Pepcans) showing negative allosteric modulation at CB1 receptors (Publications)
The alpha-hemoglobin-derived dodecapeptide RVD-hemopressin (RVDPVNFKLLSH) has been proposed to be an endogenous agonist for the cannabinoid receptor type-1 (CB1). To study this peptide we have raised
beta-Branched acyclic nucleoside analogues as inhibitors of <em>Plasmodium falciparum</em> dUTPase (Publications)
We report a series of beta-branched acyclic tritylated deoxyuridine analogues as inhibitors of Plasmodium falciparum deoxyuridine-5'-triphosphate nucleotidohydrolase (PfdUTPase), an enzyme involved in
Lung function and long term exposure to air pollutants in Switzerland. (Publications)
The effect of long-term exposure to air pollutants was studied in a cross-sectional population-based sample of adults (aged 18 to 60 yr; n = 9,651) residing in eight different areas in Switzerland. St
Follow-up of the Swiss Cohort Study on Air Pollution and Lung Diseases in Adults (SAPALDIA 2) 1991-2003: methods and characterization of participants (Publications)
OBJECTIVES: The Swiss Cohort Study on Air Pollution and Lung Diseases in Adults (SAPALDIA) was designed to investigate the health effects from long-term exposure to air pollution. METHODS: The health
The use of classification and regression trees to predict the likelihood of seasonal influenza (Publications)
BACKGROUND: Individual signs and symptoms are of limited value for the diagnosis of influenza. OBJECTIVE: To develop a decision tree for the diagnosis of influenza based on a classification and regres
Cause-specific mortality rates in sub-Saharan Africa and Bangladesh (Publications)
OBJECTIVE: To provide internationally comparable data on the frequencies of different causes of death. METHODS: We analysed verbal autopsies obtained during 1999 -2002 from 12 demographic surveillance