Female predominance and transmission distortion in the long-QT syndrome (Publications)
BACKGROUND: Congenital long-QT syndrome is a disorder resulting in ventricular arrhythmias and sudden death. The most common forms of the long-QT syndrome, types 1 and 2, are caused by mutations in th
Design, synthesis, and biological and crystallographic evaluation of novel inhibitors of <em>Plasmodium falciparum</em> enoyl-ACP-reductase... (Publications)
Malaria, a disease of worldwide significance, is responsible for over one million deaths annually. The liver-stage of Plasmodium's life cycle is the first, obligatory, but clinically silent step in ma
Substituted 2-phenyl-imidazopyridines: a new class of drug leads for human African trypanosomiasis (Publications)
A phenotypic screen of a compound library for antiparasitic activity on Trypanosoma brucei, the causative agent of human African trypanosomiasis, led to the identification of substituted 2-(3-aminophe
The prevalence and distribution of food sensitization in european adults (Publications)
BACKGROUND: Complaints of 'food allergy' are increasing. Standardized surveys of IgE sensitization to foods are still uncommon and multicountry surveys are rare. We have assessed IgE sensitization to
Acute-phase proteins and mortality in status epilepticus: a 5-year observational cohort study (Publications)
OBJECTIVE: Acute-phase proteins, such as C-reactive protein and albumin, may be related with course and outcome in status epilepticus, as changes of cytokine levels and blood-brain barrier breakdown d