A brief history of selected malaria vaccine and medical interventions pursued by the Swiss Tropical and Public Health Institute and partners,... (Publications)
In order to be successful in global health today, all the long-established European tropical research institutes had to undergo a transition which can be described as "hunter-gatherer" and descriptive
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201... (Publications)
BACKGROUND: Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress
Knowledge of antimalarials and health seeking behaviour of households in case of suspected malaria in Democratic Republic of the Congo (Publications)
(1) Background: The Democratic Republic of the Congo (DRC) is heavily affected by malaria despite availability of effective treatments. Ignorance and unrecommended behaviour toward a suspected malaria
Seroprevalence and risk factors of <em>Leptospira </em>sp. among different groups in the Jordanian population: first study (Publications)
BACKGROUND: Leptospirosis is re-emerging as a major public health problem worldwide. However, there are limited data on the disease from the Middle East, including from Jordan, despite recent outbreak
Safety, immunogenicity and efficacy of PfSPZ vaccine against malaria in infants in western Kenya: a double-blind, randomized, placebo-controlled phase... (Publications)
The radiation-attenuated Plasmodium falciparum sporozoite (PfSPZ) vaccine provides protection against P. falciparum infection in malaria-naive adults. Preclinical studies show that T cell-mediated imm
Identification of the asymptomatic <em>Plasmodium falciparum</em> and <em>Plasmodium vivax</em> gametocyte reservoir under different transmission... (Publications)
BACKGROUND: Understanding epidemiological variables affecting gametocyte carriage and density is essential to design interventions that most effectively reduce malaria human-to-mosquito transmission.
Implementation of a non-communicable disease clinic in rural Sierra Leone: early experiences and lessons learned (Publications)
This study is an evaluation of the first cohort of patients enrolled in an outpatient non-communicable disease clinic in Kono, Sierra Leone. In the first year, the clinic enrolled 916 patients. Eight
Inhibition of the SEC61 translocon by mycolactone induces a protective autophagic response controlled by EIF2S1-dependent translation that does not... (Publications)
The Mycobacterium ulcerans exotoxin, mycolactone, is responsible for the immunosuppression and tissue necrosis that characterizes Buruli ulcer. Mycolactone inhibits SEC61-dependent co-translational tr
Moderate-to-vigorous physical activity is associated with cardiorespiratory fitness among primary schoolchildren living in Côte d'Ivoire, South... (Publications)
Background: Physical inactivity and low cardiorespiratory fitness (CRF) are independent cardiovascular risk factors among children, but have rarely been investigated concurrently in sub-Saharan Africa
Low sensitivity of real time PCRs targeting retrotransposon sequences for the detection of <em>Schistosoma japonicum </em>complex DNA in human serum (Publications)
While hybridization probe-based real-time PCR assays targeting highly repetitive multi-copy genome sequences for the diagnosis of S. mansoni complex or S. haematobium complex from human serum are well