Effects of liver-stage clearance by Primaquine on gametocyte carriage of <em>Plasmodium vivax</em> and <em>P. falciparum</em> (Publications)
BACKGROUND: Primaquine (PQ) is the only currently licensed antimalarial that prevents Plasmodium vivax (Pv) relapses. It also clears mature P. falciparum (Pf) gametocytes, thereby reducing post-treatm
Antileukemic ancistrobenomine B and related 5,1′-coupled naphthylisoquinoline alkaloids from the Chinese liana <em>Ancistrocladus tectorius</em> (Publications)
A striking feature of the metabolite pattern of the Southeast Asian liana Ancistrocladus tectorius (Ancistrocladaceae) is the predominance of 5,1'-coupled naphthylisoquinoline alkaloids. About 20 alka
Target product profile for a diagnostic assay to differentiate between bacterial and non-bacterial infections and reduce antimicrobial overuse in... (Publications)
Acute fever is one of the most common presenting symptoms globally. In order to reduce the empiric use of antimicrobial drugs and improve outcomes, it is essential to improve diagnostic capabilities.
Non-uptake of HIV testing in children at risk in two urban and rural settings in Zambia: a mixed-methods study (Publications)
This article investigates reasons why children who were considered at risk of HIV were not taken for HIV testing by their caregivers. Qualitative and quantitative data collected in Zambia from 2010-11
Steroid alkaloids from <em>Holarrhena africana</em> with strong activity against <em>Trypanosoma brucei rhodesiense</em> (Publications)
In our continued search for natural compounds with activity against Trypanosoma brucei, causative agent of human African trypanosomiasis (HAT, "sleeping sickness"), we have investigated extracts from
Prevalence of diarrhoea and risk factors among children under five years old in Mbour, Senegal: a cross-sectional study (Publications)
BACKGROUND: Diarrhoeal diseases remain an important cause of mortality and morbidity among children, particularly in low- and middle-income countries. In Senegal, diarrhoea is responsible for 15% of a
Prevalence of dementia, depression, and mild cognitive impairment in a rural area of the island of Crete, Greece (Publications)
The studies on the prevalence of dementia, depression, and mild cognitive impairment (MCI) in Greece are sparse and show major variations of prevalence depending on geographical areas, nutritional hab