Traffic-related air pollution correlates with adult-onset asthma among never-smokers (Publications)
BACKGROUND: Traffic-related pollution is associated with asthma onset in children. Its effect on adult-onset asthma is poorly investigated. OBJECTIVE: We used the SAPALDIA cohort study to investigate
Development of land use regression models for nitrogen dioxide, ultrafine particles, lung deposited surface area, and four other markers of... (Publications)
BACKGROUND: Land Use Regression (LUR) is a popular method to explain and predict spatial contrasts in air pollution concentrations, but LUR models for ultrafine particles, such as particle number conc
Modification of the association between PM10 and lung function decline by cadherin 13 polymorphisms in the SAPALDIA cohort: a genome-wide interaction... (Publications)
Background: Both air pollution and genetic variation have been shown to affect lung function. Their interaction has not been studied on a genome-wide scale to date. Objectives: We aimed to identify, i
Genome-wide association and functional follow-up reveals new loci for kidney function (Publications)
Chronic kidney disease (CKD) is an important public health problem with a genetic component. We performed genome-wide association studies in up to 130,600 European ancestry participants overall, and s
Prebiotic galacto-oligosaccharides mitigate the adverse effects of iron fortification on the gut microbiome: a randomised controlled study in Kenyan... (Publications)
OBJECTIVE: Iron-containing micronutrient powders (MNPs) reduce anaemia in African infants, but the current high iron dose (12.5 mg/day) may decrease gut Bifidobacteriaceae and Lactobacillaceae, and in
Assessing potential health impacts of waste recovery and reuse business models in Hanoi, Vietnam (Publications)
OBJECTIVES: In resource-constrained settings, the recovery of nutrients and the production of energy from liquid and solid waste are important. We determined the range and magnitude of potential commu
3-hydroxy-N'-arylidenepropanehydrazonamides with halo-substituted phenanthrene scaffolds cure <em>P. berghei</em> infected mice when administered... (Publications)
Structural optimization of 3-hydroxy-N'-arylidenepropanehydrazonamides provided new analogs with nanomolar to subnanomolar antiplasmodial activity against asexual blood stages of Plasmodium falciparum
Estimation of malaria parasite reservoir coverage using reactive case detection and active community fever screening from census data with rapid... (Publications)
BACKGROUND AND METHODS: In areas where malaria transmission has been suppressed by vector control interventions many malaria control and elimination programmes are actively seeking new interventions t