Solid phase synthesis and antiprotozoal evaluation of di- and trisubstituted 5'-carboxamidoadenosine analogues (Publications)
The rapid increase of resistance to drugs commonly used in the treatment of tropical diseases such as malaria and African sleeping sickness calls for the prompt development of new safe and efficacious
Expression of the extracellular matrix protein periostin in liver tumours and bile duct carcinomas (Publications)
AIMS: To study the relevance of periostin, known to be involved in epithelial-mesenchymal transition (EMT), in hepatocellular and bile duct cancer. METHODS AND RESULTS: Immunohistochemical periostin e
Comparative immunogenicity of a PreS/S hepatitis B vaccine in non- and low responders to conventional vaccine12 (Publications)
Conventional hepatitis B vaccines do not elicit adequate antibody production in 5-10% vaccinees. This trial tests the ability of a third-generation vaccine, containing PreS1 and PreS2 antigens in addi
Antiprotozoal steroidal saponins from the marine sponge <em>Pandaros acanthifolium</em> (Publications)
The chemical composition of the Caribbean sponge Pandaros acanthifolium was reinvestigated and led to the isolation of 12 new steroidal glycosides, namely, pandarosides E-J (1-6) and their methyl este
Development of atopic dermatitis according to age of onset and association with early-life exposures (Publications)
BACKGROUND: Environmental factors can affect the development of atopic dermatitis, and this was described to be already effective during pregnancy and in early life. An important early postnatal expos
Systematic review of wireless phone use and brain cancer and other head tumors (Publications)
We conducted a systematic review of scientific studies to evaluate whether the use of wireless phones is linked to an increased incidence of the brain cancer glioma or other tumors of the head (mening
Public health importance of triggers of myocardial infarction: a comparative risk assessment (Publications)
BACKGROUND: Acute myocardial infarction is triggered by various factors, such as physical exertion, stressful events, heavy meals, or increases in air pollution. However, the importance and relevance
Availability and costs of antiepileptic drugs and quality of phenobarbital in Vientiane municipality, Lao PDR (Publications)
PURPOSE: In developing countries, availability and quality of drugs are critical factors for effective management and control of epilepsy. This study investigated the availability and costs of antiepi