Particulate matter composition and respiratory health: the PIAMA birth cohort study (Publications)
BACKGROUND:: Ambient particulate matter (PM) exposure is associated with children's respiratory health. Little is known about the importance of different PM constituents. We investigated the effects o
Anti-trypanosomal cadinanes synthesized by transannular cyclization of the natural sesquiterpene lactone nobilin (Publications)
Acid-catalyzed transannular cyclization of the germacrene-type sesquiterpene lactone nobilin 1 was investigated with the aim of obtaining new anti-trypanosomal cadinane derivatives. The reaction was r
Antibody and T cell responses associated with experimental human malaria infection or vaccination show limited relationships (Publications)
This study examined specific antibody and T cell responses associated with experimental malaria infection or malaria vaccination, in malaria-naive human volunteers within phase I/IIa vaccine trials, w
New diagnostic tools in schistosomiasis (Publications)
Schistosomiasis is a water-based parasitic disease that affects over 250 million people. Control efforts have long been in vain, which is one reason why schistosomiasis is considered a neglected tropi
One-hour rule-in and rule-out of acute myocardial infarction using high-sensitivity cardiac troponin I (Publications)
OBJECTIVE: We aimed to prospectively derive and validate a novel 1h-algorithm using high-sensitivity cardiac troponin I (hs-cTnI) for early rule-out and rule-in of acute myocardial infarction. METHODS
Clinical features for diagnosis of pneumonia in children younger than 5 years: a systematic review and meta-analysis (Publications)
BACKGROUND: Pneumonia is the biggest cause of deaths in young children in developing countries, but early diagnosis and intervention can effectively reduce mortality. We aimed to assess the diagnostic
Detection of <em>Mycobacterium tuberculosis</em> by EasyNAT diagnostic kit in sputum samples from Tanzania (Publications)
EasyNAT was evaluated for detection of tuberculosis in sputum smears of presumptive pulmonary TB patients in an African high TB and HIV setting. The sensitivity of EasyNAT was 66.7%, specificity and p