Antiprotozoal activity of bicyclic diamines with a N-methylpiperazinyl group at the bridgehead atom (Publications)
omega-Aminoacyl and -alkyl derivatives of 4-(4-methylpiperazin-1-yl)bicyclo[2.2.2]octan-2-amines and of 5-(4-methylpiperazin-1-yl)-2-azabicyclo[3.2.2]nonanes were prepared and their activities were ex
Synthesis and antiprotozoal activity of dicationic 2, 6-diphenylpyrazines and aza-analogues (Publications)
Dicationic 2,6-diphenylpyrazines, aza-analogues and prodrugs were synthesized; evaluated for DNA affinity, activity against Trypanosoma brucei rhodesiense (T. b. r.) and Plasmodium falciparum (P. f.)
<em>In vitro</em> metabolic profile and <em>in vivo</em> antischistosomal activity studies of (n6-praziquantel)Cr(Co)3 derivatives (Publications)
In vitro metabolic behavior was investigated for two chromium tricarbonyl derivatives of the antischistosomal drug praziquantel (PZQ) with the formula (?(6)-PZQ)Cr(CO)3 (1 and 2), by use of human live
Simple variables predict miserable outcome after intravenous thrombolysis (Publications)
BACKGROUND AND PURPOSE: To test the predictability of miserable outcome amongst ischaemic stroke patients receiving intravenous thrombolysis (IVT) based on a simple variables model (SVM) and to compar
The policy of free healthcare for children under the age of 6 years in Vietnam: assessment of the uptake for children hospitalised with acute... (Publications)
OBJECTIVE: To assess the proportion of, and reasons for, households not utilising the policy of free healthcare for children under 6 years of age (FCCU6) for hospitalisation with diarrhoea, and assess