Ethanolamine phosphoglycerol attachment to eEF1A is not essential for normal growth of <em>Trypanosoma brucei</em> (Publications)
Eukaryotic elongation factor 1A (eEF1A) is the only protein modified by ethanolamine phosphoglycerol (EPG). In mammals and plants, EPG is attached to conserved glutamate residues located in eEF1A doma
Discovery and evaluation of thiazinoquinones as anti-protozoal agents (Publications)
Pure compound screening has identified the dioxothiazino-quinoline-quinone ascidian metabolite ascidiathiazone A (2) to be a moderate growth inhibitor of Trypanosoma brucei rhodesiense (IC50 3.1 muM)
Emergence and spread of extensively and totally drug-resistant tuberculosis, South Africa (Publications)
Factors driving the increase in drug-resistant tuberculosis (TB) in the Eastern Cape Province, South Africa, are not understood. A convenience sample of 309 drug-susceptible and 342 multidrug-resistan
Weather and mortality: a 10 year retrospective analysis of the Nouna Health and Demographic Surveillance System, Burkina Faso (Publications)
Background: A growing body of evidence points to the emission of greenhouse gases from human activity as a key factor in climate change. This in turn affects human health and wellbeing through consequ
An analysis of interprovincial migration in Vietnam from 1989 to 2009 (Publications)
Background: In Vietnam, reports either present general patterns of internal migration or the migration characteristics of specific subgroups. Reports are often based on small numbers and do not examin
Environmental, dietary, maternal, and fetal predictors of bulky DNA adducts in cord blood: a European mother-child study (NewGeneris) (Publications)
BACKGROUND: Bulky DNA adducts reflect genotoxic exposures, have been associated with lower birthweight and may predict cancer risk. AIM: We selected factors known or hypothesized to affect in utero ad
Impact of geocoding methods on associations between long-term exposure to urban air pollution and lung function (Publications)
BACKGROUND: Errors in address geocodes may impact estimates of the effects of air pollution on health. OBJECTIVE: We investigated the impact of four geocoding techniques on the association between urb
Ancient Chinese methods are remarkably effective for the preparation of artemisinin-rich extracts of Qing Hao with potent antimalarial activity (Publications)
Ancient Chinese herbal texts as far back as the 4th Century Zhou hou bei ji fang describe methods for the use of Qing Hao (Artemisia annua) for the treatment of intermittent fevers. Today, the A. annu