Framework for rapid assessment and adoption of new vector control tools (Publications)
Evidence-informed health policy making is reliant on systematic access to, and appraisal of, the best available research evidence. This review suggests a strategy to improve the speed at which evidenc
STAT1-cooperative DNA binding distinguishes type 1 from type 2 interferon signaling (Publications)
STAT1 is an indispensable component of a heterotrimer (ISGF3) and a STAT1 homodimer (GAF) that function as transcription regulators in type 1 and type 2 interferon signaling, respectively. To investig
Reactivity to accelerometer measurement of children and adolescents (Publications)
PURPOSE: Awareness of being monitored can influence participants' habitual physical activity (PA) behavior. This reactivity effect may threaten the validity of PA assessment. Reports on reactivity whe
A broadly-protective vaccine against meningococcal disease in sub-Saharan Africa based on generalised modules for membrane antigens (GMMA) (Publications)
INTRODUCTION: Neisseria meningitidis causes epidemics of meningitis in sub-Saharan Africa. These have mainly been caused by capsular group A strains, but W and X strains are increasingly contributing
2,4-diaminothienopyrimidines as orally active antimalarial agents (Publications)
A novel series of 2,4-diaminothienopyrimidines with potential as antimalarials was identified from whole-cell high-throughput screening of a SoftFocus ion channel library. Synthesis and structure-acti
<em>Paragonimus paishuihoensis</em> metacercariae in freshwater crabs, <em>Potamon lipkei</em>, in Vientiane Province, Lao PDR (Publications)
Among Paragonimus species, P. paishuihoensis is one of the most mysterious and poorly understood species. Metacercariae are characterized by having a unique dendritically branched excretory bladder. H
<em>In vitro</em> efficacy of dicationic compounds and mefloquine enantiomers against <em>Echinococcus multilocularis</em> metacestodes (Publications)
The current chemotherapy of alveolar echinococcosis (AE) is based on benzimidazoles such as albendazole and has been shown to be parasitostatic rather than parasiticidal, requiring lifelong duration.