Time trends of positivity rates from foodborne pathogen testing in Switzerland, 2003 to 2012 (Publications)
BACKGROUND: Campylobacteriosis and salmonellosis are important foodborne diseases in Europe, including in Switzerland. In 2014, notification rates for Switzerland were 92.9 per 100 000 population for
Identification of steroid-like natural products as antiplasmodial agents by 2D and 3D similarity-based virtual screening (Publications)
The emergence of drug resistance in Plasmodium falciparum to available antimalarial drugs has challenged current antimalarial treatments. New antimalarials, particularly those with novel mechanisms of
Sporozoite immunization: innovative translational science to support the fight against malaria (Publications)
INTRODUCTION: Malaria, a devastating febrile illness caused by protozoan parasites, sickened 247,000,000 people in 2021 and killed 619,000, mostly children and pregnant women in sub-Saharan Africa. A
Genetic validation of <em>Pf</em>FKBP35 as an antimalarial drug target (Publications)
Plasmodium falciparum accounts for the majority of over 600,000 malaria-associated deaths annually. Parasites resistant to nearly all antimalarials have emerged and the need for drugs with alternative
Community-based type 2 diabetes care by lay village health workers in rural Lesotho: protocol for a cluster-randomized trial within the ComBaCaL... (Publications)
BACKGROUND: Type 2 diabetes (T2D) poses a growing public health burden, especially in low- and middle-income countries (LMICs). Task-shifting to lay village health workers (VHWs) and the use of digita
Baseline liver ultrasound findings in preschool children from the praziquantel in preschoolers trial in Lake Albert, Uganda (Publications)
BACKGROUND: Periportal fibrosis is a late-stage manifestation of chronic infection with Schistosoma mansoni. Praziquantel (PZQ), the only drug available for the treatment of schistosomiasis, has limit