Exploring prospects of novel drugs for tuberculosis (Publications)
Tuberculosis remains a disease with an enormous impact on public health worldwide. With the continuously increasing epidemic of drug-resistant tuberculosis, new drugs are desperately needed. However,
Prognostic value of stress testing in patients over 75 years of age with chronic angina (Publications)
STUDY OBJECTIVES: To define the prognostic value of stress testing (STRT) in patients > or= 75 years of age. DESIGN: Multicenter prospective randomized trial. SETTING: Tertiary care centers. PATIENTS:
Antitrypanosomal sesquiterpene lactones from <em>Saussurea costus</em> (Publications)
In the course of a larger screen of 1800 plant and fungal extracts, the ethyl acetate extract of Saussurea costus roots potently inhibited the growth of Trypanosoma brucei rhodesiense. Subsequent HPLC
Methotrexate and aminopterin lack in vivo antimalarial activity against murine malaria species (Publications)
The antifolate anticancer drug methotrexate (MTX) has potent activity against Plasmodium falciparum in vitro. Experience of its use in the treatment of rheumatoid arthritis indicates that it could be
Use of transition probabilities to estimate the effect of smoking on the duration of episodes of respiratory symptoms in diary data: the Swiss Study... (Publications)
Incompletely documented symptom episodes pose methodological problems in the analysis of diary data. The aim of this study was to develop a method of estimating the average durations of symptomatic an
Selection bias of elderly patients with chronic angina referred for catheterization (Publications)
BACKGROUND: Registry patients are generally older and more sick than patients enrolled in trials questioning the generalizability of trial results. We assessed whether such a selection bias also exist