Steroid alkaloids from <em>Holarrhena africana</em> with strong activity against <em>Trypanosoma brucei rhodesiense</em> (Publications)
In our continued search for natural compounds with activity against Trypanosoma brucei, causative agent of human African trypanosomiasis (HAT, "sleeping sickness"), we have investigated extracts from
Prevalence of diarrhoea and risk factors among children under five years old in Mbour, Senegal: a cross-sectional study (Publications)
BACKGROUND: Diarrhoeal diseases remain an important cause of mortality and morbidity among children, particularly in low- and middle-income countries. In Senegal, diarrhoea is responsible for 15% of a
Land use regression models for alkylbenzenes in a Middle Eastern megacity: Tehran Study of Exposure Prediction for Environmental Health Research... (Publications)
Land use regression (LUR) has not been applied thus far to ambient alkylbenzenes in highly polluted megacities. We advanced LUR models for benzene, toluene, ethylbenzene, p-xylene, m-xylene, o-xylene
Medical use of cannabis in Switzerland: analysis of approved exceptional licences (Publications)
AIMS OF THE STUDY: In recent years, the Swiss Federal Office of Public Health (FOPH) granted exceptional licenses for the medical use of cannabinoids, typically for 6 months with possible extensions.
Transcriptional profiling defines dynamics of parasite tissue sequestration during malaria infection (Publications)
BACKGROUND: During intra-erythrocytic development, late asexually replicating Plasmodium falciparum parasites sequester from peripheral circulation. This facilitates chronic infection and is linked to
Synthesis and potent antiprotozoal activity of mono/di amidino 2-anilinobenz-imidazoles versus <em>Plasmodium falciparum</em> and <em>Trypanosoma... (Publications)
A series of mono and dicationic new 2-anilinobenzimidazole carboxamidines were prepared in a four step process starting from 4-amino-3-nitrobenzonitrile and corresponding o-phenylenediamines. Their an